| Host: | Rabbit |
| Applications: | IHC-P/ELISA |
| Reactivity: | Human |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | IHC-P:1:50-1:100ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | LAMB3 |
| Gene ID: | 3914 |
| Uniprot ID: | LAMB3_HUMAN |
| Immunogen Region: | 18-230 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 18-230 of human LAMB3 (NP_000219.2). |
| Immunogen Sequence: | QQACSRGACYPPVGDLLVGR TRFLRASSTCGLTKPETYCT QYGEWQMKCCKCDSRQPHNY YSHRVENVASSSGPMRWWQS QNDVNPVSLQLDLDRRFQLQ EVMMEFQGPMPAGMLIERSS DFGKTWRVYQYLAADCTSTF PRVRQGRPQSWQDVRCQSLP QRPNARLNGGKVQLNLMDLV SGIPATQSQKIQEVGEITNL RVNFTRLAPVPQR |
| Tissue Specificity | Found in the basement membranes (major component). |
| Function | Binding to cells via a high affinity receptor, laminin is thought to mediate the attachment, migration and organization of cells into tissues during embryonic development by interacting with other extracellular matrix components. |
| Protein Name | Laminin Subunit Beta-3Epiligrin Subunit BataKalinin B1 ChainKalinin Subunit BetaLaminin B1k ChainLaminin-5 Subunit BetaNicein Subunit Beta |
| Database Links | Reactome: R-HSA-1474228Reactome: R-HSA-2022090Reactome: R-HSA-2214320Reactome: R-HSA-3000157Reactome: R-HSA-3000171Reactome: R-HSA-446107Reactome: R-HSA-8874081 |
| Cellular Localisation | SecretedExtracellular SpaceExtracellular MatrixBasement Membrane |
| Alternative Antibody Names | Anti-Laminin Subunit Beta-3 antibodyAnti-Epiligrin Subunit Bata antibodyAnti-Kalinin B1 Chain antibodyAnti-Kalinin Subunit Beta antibodyAnti-Laminin B1k Chain antibodyAnti-Laminin-5 Subunit Beta antibodyAnti-Nicein Subunit Beta antibodyAnti-LAMB3 antibodyAnti-LAMNB1 antibody |
Information sourced from Uniprot.org
