Anti-LAMA4 antibody (1-100) (STJ117481)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal LAMA4 (1-100) antibody for use in WB and ELISA in human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:200-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | LAMA4 |
| Gene ID | 3910 |
| Uniprot ID | LAMA4_HUMAN |
| Immunogen Region | 1-100 |
| Immunogen Sequence | MALSSAWRSVLPLWLLWSAA CSRAASGDDNAFPFDIEGSS AVGRQDPPETSEPRVALGRL PPAAEVQCPCHCHPAGAPAP PRAVPHSSFSLSPPLSSPQC |
| Specificity | A synthetic peptide corresponding to a sequence within amino acids 1-100 of human LAMA4 (NP_001098678.1). |
Additional Info
| Tissue Specificity | Detected in placenta (at protein level). Detected in fibroblasts and urine (at protein level). In adult, strong expression in heart, lung, ovary small and large intestines, placenta, liver.weak or no expression in skeletal muscle, kidney, pancreas, testis, prostate, brain. High expression in fetal lung and kidney. Expression in fetal and newborn tissues is observed in certain mesenchymal cells in tissues such as smooth muscle and dermis. |
| Function | Binding to cells via a high affinity receptor, laminin is thought to mediate the attachment, migration and organization of cells into tissues during embryonic development by interacting with other extracellular matrix components. |
| Protein Name | Laminin Subunit Alpha-4Laminin-14 Subunit AlphaLaminin-8 Subunit AlphaLaminin-9 Subunit Alpha |
| Database Links | Reactome: R-HSA-3000157Reactome: R-HSA-3000171Reactome: R-HSA-3000178Reactome: R-HSA-8874081Reactome: R-HSA-9913351 |
| Cellular Localisation | SecretedExtracellular SpaceExtracellular MatrixBasement MembraneMajor Basement Membrane Component |
| Alternative Antibody Names | Anti-Laminin Subunit Alpha-4 antibodyAnti-Laminin-14 Subunit Alpha antibodyAnti-Laminin-8 Subunit Alpha antibodyAnti-Laminin-9 Subunit Alpha antibodyAnti-LAMA4 antibody |
Information sourced from Uniprot.org