• STJ73546 (1µg/ml) staining of MCF7 cell lysate (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.

Anti-Lactadherin antibody (Internal) (STJ73546)

SKU:
STJ73546-100

£303.50
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Host: Goat
Applications: Pep-ELISA/WB
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Goat polyclonal antibody anti-Lactadherin (Internal) is suitable for use in ELISA and Western Blot research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA
Purification: Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Concentration: 0.5 mg/mL
Dilution Range: WB-1-3µg/ml
ELISA-antibody detection limit dilution 1:16000.
Storage Instruction: Store at-20°C on receipt and minimise freeze-thaw cycles.
Gene Symbol: MFGE8
Gene ID: 4240
Uniprot ID: MFGM_HUMAN
Immunogen Region: Internal
Accession Number: NP_005919.2; NP_001108086.1
Specificity: This antibody is expected to recognize both reported isoforms (NP_005919.2; NP_001108086.1).
Immunogen Sequence: KNNSIPDKQITAS
Post Translational Modifications Medin has a ragged N-terminus with minor species starting at Pro-264 and Gly-273.
Function Plays an important role in the maintenance of intestinal epithelial homeostasis and the promotion of mucosal healing. Promotes VEGF-dependent neovascularization. Contributes to phagocytic removal of apoptotic cells in many tissues. Specific ligand for the alpha-v/beta-3 and alpha-v/beta-5 receptors. Also binds to phosphatidylserine-enriched cell surfaces in a receptor-independent manner. Zona pellucida-binding protein which may play a role in gamete interaction. Medin: Main constituent of aortic medial amyloid.
Protein Name Lactadherin
Breast Epithelial Antigen Ba46
Hmfg
Mfgm
Milk Fat Globule-Egf Factor 8
Mfg-E8
Sed1 Cleaved Into - Lactadherin Short Form - Medin
Database Links Reactome: R-HSA-381426
Reactome: R-HSA-8957275
Reactome: R-HSA-977225
Cellular Localisation Membrane
Peripheral Membrane Protein
Secreted
Cytoplasmic Vesicle
Secretory Vesicle
Acrosome Membrane
Located In The Acrosomal Region Of Zona-Pellucida Bound Sperm
Alternative Antibody Names Anti-Lactadherin antibody
Anti-Breast Epithelial Antigen Ba46 antibody
Anti-Hmfg antibody
Anti-Mfgm antibody
Anti-Milk Fat Globule-Egf Factor 8 antibody
Anti-Mfg-E8 antibody
Anti-Sed1 Cleaved Into - Lactadherin Short Form - Medin antibody
Anti-MFGE8 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance