• Western blot analysis of lysates from K562 cells, using CD171/N-CAML1 Antibody. The lane on the right is blocked with the synthesized peptide.
  • Western blot analysis of Jurkat cells using NCAM-L1 Polyclonal Antibody
  • Immunofluorescence analysis of HepG2 cells, using CD171/N-CAML1 Antibody. The picture on the right is blocked with the synthesized peptide.
  • Western blot analysis of various cells using NCAM-L1 Polyclonal Antibody

Anti-L1CAM antibody (1147-1196) (STJ94355)

SKU:
STJ94355

$64.80 - $340.20
Current Stock:
Host: Rabbit
Applications: WB/IHC/IF/ELISA
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-Neural cell adhesion molecule L1 (1147-1196) is suitable for use in Western Blot, Immunohistochemistry, Immunofluorescence and ELISA research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration: 1 mg/mL
Dilution Range: WB 1:500-1:2000
IHC 1:100-1:300
IF 1:200-1:1000
ELISA 1:20000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: L1CAM
Gene ID: 3897
Uniprot ID: L1CAM_HUMAN
Immunogen Region: 1147-1196
Specificity: NCAM-L1 Polyclonal Antibody detects endogenous levels of NCAM-L1 protein.
Immunogen: The antiserum was produced against synthesized peptide derived from human CD171/N-CAML1. AA range:1147-1196
Function Neural cell adhesion molecule involved in the dynamics of cell adhesion and in the generation of transmembrane signals at tyrosine kinase receptors. During brain development, critical in multiple processes, including neuronal migration, axonal growth and fasciculation, and synaptogenesis. In the mature brain, plays a role in the dynamics of neuronal structure and function, including synaptic plasticity.
Protein Name Neural Cell Adhesion Molecule L1
N-Cam-L1
Ncam-L1
Cd Antigen Cd171
Database Links Reactome: R-HSA-210991
Reactome: R-HSA-373760
Reactome: R-HSA-437239
Reactome: R-HSA-445095
Reactome: R-HSA-445144
Cellular Localisation Cell Membrane
Single-Pass Type I Membrane Protein
Cell Projection
Growth Cone
Axon
Dendrite
Colocalized With Shtn1 In Close Apposition With Actin Filaments In Filopodia And Lamellipodia Of Axonalne Growth Cones Of Hippocampal Neurons
In Neurons
Detected Predominantly In Axons And Cell Body
Weak Localization To Dendrites
Alternative Antibody Names Anti-Neural Cell Adhesion Molecule L1 antibody
Anti-N-Cam-L1 antibody
Anti-Ncam-L1 antibody
Anti-Cd Antigen Cd171 antibody
Anti-L1CAM antibody
Anti-CAML1 antibody
Anti-MIC5 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance