| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human/Mouse/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-Keratinocyte-associated protein 2 (39-89 aa) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: |
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: |
1 mg/mL |
| Dilution Range: |
WB 1:500-2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
KRTCAP2 |
| Gene ID: |
200185 |
| Uniprot ID: |
KTAP2_HUMAN |
| Immunogen Region: |
39-89 aa |
| Specificity: |
This antibody detects endogenous levels of KTAP2 at Human/Mouse/Rat |
| Immunogen: |
Synthesized peptide derived from the human KTAP2 at the amino acid range 39-89 |
| Function | Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol-pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the endoplasmic reticulum (ER). All subunits are required for a maximal enzyme activity. May be involved in N-glycosylation of APP (amyloid-beta precursor protein). Can modulate gamma-secretase cleavage of APP by enhancing endoprotelysis of PSEN1. |
| Protein Name | Keratinocyte-Associated Protein 2Kcp-2Dolichyl-Diphosphooligosaccharide--Protein Glycosyltransferase Subunit Kcp2Oligosaccharyl Transferase Subunit Kcp2 |
| Cellular Localisation | Endoplasmic ReticulumEndoplasmic Reticulum MembraneMulti-Pass Membrane Protein |
| Alternative Antibody Names | Anti-Keratinocyte-Associated Protein 2 antibodyAnti-Kcp-2 antibodyAnti-Dolichyl-Diphosphooligosaccharide--Protein Glycosyltransferase Subunit Kcp2 antibodyAnti-Oligosaccharyl Transferase Subunit Kcp2 antibodyAnti-KRTCAP2 antibodyAnti-KCP2 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
