Anti-KRTCAP2 antibody (39-89 aa) (STJ193973)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthesized peptide derived from the human KTAP2 at the amino acid range 39-89
General Information
| Short Description | Rabbit polyclonal anti-Keratinocyte-associated protein 2 (39-89 aa) for use in WB in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | KRTCAP2 |
| Gene ID | 200185 |
| Uniprot ID | KTAP2_HUMAN |
| Immunogen | Synthesized peptide derived from the human KTAP2 at the amino acid range 39-89 |
| Immunogen Region | 39-89 aa |
| Specificity | This antibody detects endogenous levels of KTAP2 at Human/Mouse/Rat |
Additional Info
| Function | Subunit of STT3A-containing oligosaccharyl transferase (OST-A) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol-pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the endoplasmic reticulum (ER). Within the OST-A complex, acts as an adapter that anchors the OST-A complex to the Sec61 complex. May be involved in N-glycosylation of APP (amyloid-beta precursor protein). Can modulate gamma-secretase cleavage of APP by enhancing endoprotelysis of PSEN1. |
| Protein Name | Dolichyl-Diphosphooligosaccharide--Protein Glycosyltransferase Subunit Kcp2Oligosaccharyl Transferase Subunit Kcp2Keratinocyte-Associated Protein 2Kcp-2 |
| Database Links | |
| Cellular Localisation | Endoplasmic ReticulumEndoplasmic Reticulum MembraneMulti-Pass Membrane Protein |
| Alternative Antibody Names | Anti-Dolichyl-Diphosphooligosaccharide--Protein Glycosyltransferase Subunit Kcp2 antibodyAnti-Oligosaccharyl Transferase Subunit Kcp2 antibodyAnti-Keratinocyte-Associated Protein 2 antibodyAnti-Kcp-2 antibodyAnti-KRTCAP2 antibodyAnti-KCP2 antibody |
Information sourced from Uniprot.org