| Short Description : | Rabbit polyclonal anti-Keratin-associated protein 12-1 (22-72 aa) for use in IHC and IF in Human and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications: | IHC/IF |
| Host: | Rabbit |
| Reactivity: | Human/Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Isotype: | IgG |
| Conjugation: | Unconjugated |
| Concentration: | 1 mg/mL |
| Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range: | IHC-P 1:50-200IF 1:50-200 |
| Formulation: | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | KRTAP12-1 |
| Gene ID: | 353332 |
| Uniprot ID: | KR121_HUMAN |
| Immunogen: | Synthesized peptide derived from the human KR121 at the amino acid range 22-72 |
| Immunogen Region: | 22-72 aa |
| Specificity: | This antibody detects endogenous levels of KR121 at Human/Mouse |
| Function | In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin-associated proteins (KRTAP), which are essential for the formation of a rigid and resistant hair shaft through their extensive disulfide bond cross-linking with abundant cysteine residues of hair keratins. The matrix proteins include the high-sulfur and high-glycine-tyrosine keratins. |
| Protein Name | Keratin-Associated Protein 12-1High Sulfur Keratin-Associated Protein 12.1Keratin-Associated Protein 12.1 |
| Database Links | Reactome: R-HSA-6805567 |
| Cellular Localisation | |
| Alternative Antibody Names | Anti-Keratin-Associated Protein 12-1 antibodyAnti-High Sulfur Keratin-Associated Protein 12.1 antibodyAnti-Keratin-Associated Protein 12.1 antibodyAnti-KRTAP12-1 antibodyAnti-KAP12.1 antibodyAnti-KRTAP12.1 antibody |
Information sourced from Uniprot.org
