Anti-KRTAP12-1 antibody (22-72 aa) (STJ196594)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthesized peptide derived from the human KR121 at the amino acid range 22-72
General Information
| Short Description | Rabbit polyclonal anti-Keratin-associated protein 12-1 (22-72 aa) for use in IHC and IF in Human and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | IHC/IF |
| Host | Rabbit |
| Reactivity | Human/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | IHC-P 1:50-200IF 1:50-200 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20ยฐC for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | KRTAP12-1 |
| Gene ID | 353332 |
| Uniprot ID | KR121_HUMAN |
| Immunogen | Synthesized peptide derived from the human KR121 at the amino acid range 22-72 |
| Immunogen Region | 22-72 aa |
| Specificity | This antibody detects endogenous levels of KR121 at Human/Mouse |
Additional Info
| Function | In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin-associated proteins (KRTAP), which are essential for the formation of a rigid and resistant hair shaft through their extensive disulfide bond cross-linking with abundant cysteine residues of hair keratins. The matrix proteins include the high-sulfur and high-glycine-tyrosine keratins. |
| Protein Name | Keratin-Associated Protein 12-1High Sulfur Keratin-Associated Protein 12.1Keratin-Associated Protein 12.1 |
| Database Links | Reactome: R-HSA-6805567 |
| Cellular Localisation | |
| Alternative Antibody Names | Anti-Keratin-Associated Protein 12-1 antibodyAnti-High Sulfur Keratin-Associated Protein 12.1 antibodyAnti-Keratin-Associated Protein 12.1 antibodyAnti-KRTAP12-1 antibodyAnti-KAP12.1 antibodyAnti-KRTAP12.1 antibody |
Information sourced from Uniprot.org