Anti-KRT6A antibody (2-100 aa) [ABT052] (STJ196732)
SPECIFICATIONS
ClonalityMonoclonal
HostMouse
ConjugationUnconjugated
IsotypeIgG2ak
ImmunogenSynthesized peptide derived from the human Cytokeratin 6 at the amino acid range 2-100
General Information
| Short Description | Mouse monoclonal anti-Keratin, type II cytoskeletal 6A (2-100 aa) for use in IHC and WB in Human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | IHC/WB |
| Host | Mouse |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | ABT052 |
| Isotype | IgG2ak |
| Conjugation | Unconjugated |
| Purification | The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen. |
| Dilution Range | IHC-P 1:200-400WB 500-1000 |
| Formulation | Liquid in PBS pH7.2, 0.03% Proclin 300, with stabilizing protein. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | KRT6A |
| Gene ID | 3853 |
| Uniprot ID | K2C6A_HUMAN |
| Immunogen | Synthesized peptide derived from the human Cytokeratin 6 at the amino acid range 2-100 |
| Immunogen Region | 2-100 aa |
| Specificity | The antibody can specifically recognize human CK6 protein, and shows no cross reaction with CK5. In western blotting of Hela, A431, A549 and HEK293 cell lysates, the antibody can label a 56 kDa band c |
Additional Info
| Function | Epidermis-specific type I keratin involved in wound healing. Involved in the activation of follicular keratinocytes after wounding, while it does not play a major role in keratinocyte proliferation or migration. Participates in the regulation of epithelial migration by inhibiting the activity of SRC during wound repair. |
| Protein Name | Keratin - Type Ii Cytoskeletal 6aCytokeratin-6aCk-6aCytokeratin-6dCk-6dKeratin-6aK6aType-Ii Keratin Kb6Allergen Hom S 5 |
| Database Links | Reactome: R-HSA-6805567Reactome: R-HSA-6809371 |
| Cellular Localisation | |
| Alternative Antibody Names | Anti-Keratin - Type Ii Cytoskeletal 6a antibodyAnti-Cytokeratin-6a antibodyAnti-Ck-6a antibodyAnti-Cytokeratin-6d antibodyAnti-Ck-6d antibodyAnti-Keratin-6a antibodyAnti-K6a antibodyAnti-Type-Ii Keratin Kb6 antibodyAnti-Allergen Hom S 5 antibodyAnti-KRT6A antibodyAnti-K6A antibodyAnti-KRT6D antibody |
Information sourced from Uniprot.org