Anti-KRT13 antibody (269-458) (STJ118821)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal KRT13 (269-458) antibody for use in WB, IHC-P, IF, ICC and ELISA in human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IHC-P/IF/ICC/ELISA |
| Host | Rabbit |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:2000IHC-P:1:50-1:100IF/ICC:1:50-1:100ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | KRT13 |
| Gene ID | 3860 |
| Uniprot ID | K1C13_HUMAN |
| Immunogen Region | 269-458 |
| Immunogen Sequence | DLTRVLAEMREQYEAMAERN RRDAEEWFHAKSAELNKEVS TNTAMIQTSKTEITELRRTL QGLEIELQSQLSMKAGLENT VAETECRYALQLQQIQGLIS SIEAQLSELRSEMECQNQEY KMLLDIKTRLEQEIATYRSL LEGQDAKMIGFPSSAGSVSP RSTSVTTTSSASVTTTSNAS GRRTSDVRRP |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 269-458 of human Cytokeratin 13 (Cytokeratin 13 (KRT13) ) (NP_705694.2). |
Additional Info
| Tissue Specificity | Expressed in some epidermal sweat gland ducts (at protein level) and in exocervix, esophagus and placenta. |
| Post Translational Modifications | O-glycosylated.glycans consist of single N-acetylglucosamine residues. |
| Function | Type 1 keratin (Probable). Maintains postnatal tongue mucosal cell homeostasis and tissue organization in response to mechanical stress, potentially via regulation of the G1/S phase cyclins CCNE1 and CCNE2. |
| Protein Name | Keratin - Type I Cytoskeletal 13Cytokeratin-13Ck-13Keratin-13K13 |
| Database Links | Reactome: R-HSA-6805567Reactome: R-HSA-6809371 |
| Cellular Localisation | |
| Alternative Antibody Names | Anti-Keratin - Type I Cytoskeletal 13 antibodyAnti-Cytokeratin-13 antibodyAnti-Ck-13 antibodyAnti-Keratin-13 antibodyAnti-K13 antibodyAnti-KRT13 antibody |
Information sourced from Uniprot.org