Anti-KRR1 antibody (1-381) (STJ116243)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal KRR1 (1-381) antibody for use in WB, IF, ICC and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IF/ICC/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:2000IF/ICC:1:50-1:200ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | KRR1 |
| Gene ID | 11103 |
| Uniprot ID | KRR1_HUMAN |
| Immunogen Region | 1-381 |
| Immunogen Sequence | MASPSLERPEKGAGKSEFRN QKPKPENQDESELLTVPDGW KEPAFSKEDNPRGLLEESSF ATLFPKYREAYLKECWPLVQ KALNEHHVNATLDLIEGSMT VCTTKKTFDPYIIIRARDLI KLLARSVSFEQAVRILQDDV ACDIIKIGSLVRNKERFVKR RQRLIGPKGSTLKALELLTN CYIMVQGNTVSAIGPFSGLK EVRKVVLDTMKNIHPIYNIK SLMIKRELAKDSELRSQSW |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 1-381 of human KRR1 (NP_008974.5). |
Additional Info
| Function | Part of the small subunit (SSU) processome, first precursor of the small eukaryotic ribosomal subunit. During the assembly of the SSU processome in the nucleolus, many ribosome biogenesis factors, an RNA chaperone and ribosomal proteins associate with the nascent pre-rRNA and work in concert to generate RNA folding, modifications, rearrangements and cleavage as well as targeted degradation of pre-ribosomal RNA by the RNA exosome. |
| Protein Name | Krr1 Small Subunit Processome Component HomologHiv-1 Rev-Binding Protein 2Krr-R Motif-Containing Protein 1Rev-Interacting Protein 1Rip-1 |
| Database Links | Reactome: R-HSA-6790901Reactome: R-HSA-6791226 |
| Cellular Localisation | NucleusNucleolusCytoplasm(Microbial Infection) Translocates From Cytoplasm To Nucleus After Exposure To Hiv-1 Virus Or Hiv-1 Protein Vpr Or Induction By Hydrocortisone And Dexamethasone In The Absence Of Hiv-1 Protein Vpr |
| Alternative Antibody Names | Anti-Krr1 Small Subunit Processome Component Homolog antibodyAnti-Hiv-1 Rev-Binding Protein 2 antibodyAnti-Krr-R Motif-Containing Protein 1 antibodyAnti-Rev-Interacting Protein 1 antibodyAnti-Rip-1 antibodyAnti-KRR1 antibodyAnti-HRB2 antibody |
Information sourced from Uniprot.org