| Host: | Goat |
| Applications: | Pep-ELISA |
| Reactivity: | Human |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Goat polyclonal antibody anti-KLRG1 (N-Term) is suitable for use in ELISA research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA |
| Purification: | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Concentration: | 0.5 mg/mL |
| Dilution Range: | Peptide ELISA: antibody detection limit dilution 1:1000.WB: Preliminary experiments in Human Lymph Node and Spleen lysates gave no specific signal but low background (at antibody concentration up to 1µg/ml). |
| Storage Instruction: | Store at-20°C on receipt and minimise freeze-thaw cycles. |
| Gene Symbol: | KLRG1 |
| Gene ID: | 10219 |
| Uniprot ID: | KLRG1_HUMAN |
| Immunogen Region: | N-Term |
| Accession Number: | NP_005801.3 |
| Immunogen Sequence: | QAQNDYGPQQKS |
| Function | Plays an inhibitory role on natural killer (NK) cells and T-cell functions upon binding to their non-MHC ligands. May mediate missing self recognition by binding to a highly conserved site on classical cadherins, enabling it to monitor expression of E-cadherin/CDH1, N-cadherin/CDH2 and R-cadherin/CDH4 on target cells. |
| Protein Name | Killer Cell Lectin-Like Receptor Subfamily G Member 1C-Type Lectin Domain Family 15 Member AItim-Containing Receptor Mafa-LMafa-Like ReceptorMast Cell Function-Associated Antigen |
| Database Links | Reactome: R-HSA-198933 |
| Cellular Localisation | Cell MembraneSingle-Pass Type Ii Membrane Protein |
| Alternative Antibody Names | Anti-Killer Cell Lectin-Like Receptor Subfamily G Member 1 antibodyAnti-C-Type Lectin Domain Family 15 Member A antibodyAnti-Itim-Containing Receptor Mafa-L antibodyAnti-Mafa-Like Receptor antibodyAnti-Mast Cell Function-Associated Antigen antibodyAnti-KLRG1 antibodyAnti-CLEC15A antibodyAnti-MAFA antibodyAnti-MAFAL antibody |
Information sourced from Uniprot.org