Anti-KLRG1 antibody [DM184] (STJA0038153)
SPECIFICATIONS
ClonalityMonoclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenRecombinant human KLRG1 protein
General Information
| Short Description | Rabbit monoclonal anti-KLRG1 for use in FC and ELISA in Human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | FC/ELISA |
| Host | Rabbit |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | DM184 |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Purification | Affinity Chromatography |
| Dilution Range | FC 1:50-1:100ELISA 1:10000 |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3. |
| Storage Instruction | Store at 4°C short term. Aliquot and store at-20°C long term. Avoid freeze/thaw cycles. |
Target Information
| Gene Symbol | KLRG1 |
| Gene ID | 10219 |
| Uniprot ID | KLRG1_HUMAN |
| Immunogen | Recombinant human KLRG1 protein |
Additional Info
| Tissue Specificity | Expressed specifically on natural killer (NK) cells and T-cells, mainly CD8 T-cells. |
| Function | Plays an inhibitory role on natural killer (NK) cells and T-cell functions upon binding to their non-MHC ligands. May mediate missing self recognition by binding to a highly conserved site on classical cadherins, enabling it to monitor expression of E-cadherin/CDH1, N-cadherin/CDH2 and R-cadherin/CDH4 on target cells. |
| Protein Name | Killer Cell Lectin-Like Receptor Subfamily G Member 1C-Type Lectin Domain Family 15 Member AItim-Containing Receptor Mafa-LMafa-Like ReceptorMast Cell Function-Associated Antigen |
| Database Links | Reactome: R-HSA-198933 |
| Cellular Localisation | Cell MembraneSingle-Pass Type Ii Membrane Protein |
| Alternative Antibody Names | Anti-Killer Cell Lectin-Like Receptor Subfamily G Member 1 antibodyAnti-C-Type Lectin Domain Family 15 Member A antibodyAnti-Itim-Containing Receptor Mafa-L antibodyAnti-Mafa-Like Receptor antibodyAnti-Mast Cell Function-Associated Antigen antibodyAnti-KLRG1 antibodyAnti-CLEC15A antibodyAnti-MAFA antibodyAnti-MAFAL antibody |
Information sourced from Uniprot.org