Anti-KLK7 antibody [SAA0869] (STJA0019664)
SPECIFICATIONS
ClonalityMonoclonal
HostMouse
ConjugationUnconjugated
IsotypeIgG2a
General Information
| Short Description | Mouse monoclonal Kallikrein-7 antibody for use in Blocking and ELISA in human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | Blocking/ELISA |
| Host | Mouse |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO) MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS |
Product Properties
| Clonality | Monoclonal |
| Clone ID | SAA0869 |
| Isotype | IgG2a |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | Protein A/G purified from cell culture supernatant |
| Formulation | 0.01M PBS, pH 7.4. |
| Storage Instruction | Suitable for storage at +4°C between 1-2 weeks For longer term store at-20°C for up to 12 months |
Target Information
| Gene Symbol | KLK7 |
| Gene ID | 5650 |
| Uniprot ID | KLK7_HUMAN |
Additional Info
| Function | May catalyze the degradation of intercellular cohesive structures in the cornified layer of the skin in the continuous shedding of cells from the skin surface. Specific for amino acid residues with aromatic side chains in the P1 position. Cleaves insulin A chain at '14-Tyr-|-Gln-15' and insulin B chain at '6-Leu-|-Cys-7', '16-Tyr-|-Leu-17', '25-Phe-|-Tyr-26' and '26-Tyr-|-Thr-27'. Could play a role in the activation of precursors to inflammatory cytokines. |
| Protein Name | Kallikrein-7Hk7Serine Protease 6Stratum Corneum Chymotryptic EnzymeHscce |
| Database Links | Reactome: R-HSA-1474228Reactome: R-HSA-9725554 |
| Cellular Localisation | SecretedIn Ovarian CarcinomaSecreted And Also Observed At The Apical Membrane And In Cytoplasm At The Invasive Front |
| Alternative Antibody Names | Anti-Kallikrein-7 antibodyAnti-Hk7 antibodyAnti-Serine Protease 6 antibodyAnti-Stratum Corneum Chymotryptic Enzyme antibodyAnti-Hscce antibodyAnti-KLK7 antibodyAnti-PRSS6 antibodyAnti-SCCE antibody |
Information sourced from Uniprot.org