Anti-KLHL8 antibody (271-620) (STJ117116)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal KLHL8 (271-620) antibody for use in WB, IF, ICC and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IF/ICC/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:2000IF/ICC:1:50-1:200ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20ยฐC for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | KLHL8 |
| Gene ID | 57563 |
| Uniprot ID | KLHL8_HUMAN |
| Immunogen Region | 271-620 |
| Immunogen Sequence | AKEQIVKQNLKCRDLLDEAR NYHLHLSSRAVPDFEYSIRT TPRKHTAGVLFCVGGRGGSG DPFRSIECYSINKNSWFFGP EMNSRRRHVGVISVEGKVYA VGGHDGNEHLGSMEMFDPLT NKWMMKASMNTKRRGIALAS LGGPIYAIGGLDDNTCFNDV ERYDIESDQWSTVAPMNTPR GGVGSVALVNHVYAVGGNDG MASLSSVERYDPHLDKWIEV KEMGQRRAGNGVSKLHGCL |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 271-620 of human KLHL8 (NP_065854.3). |
Additional Info
| Function | Substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin ligase complex required for The BCR(KLHL8) ubiquitin ligase complex mediates ubiquitination and degradation of RAPSN. |
| Protein Name | Kelch-Like Protein 8 |
| Database Links | |
| Cellular Localisation | |
| Alternative Antibody Names | Anti-Kelch-Like Protein 8 antibodyAnti-KLHL8 antibodyAnti-KIAA1378 antibody |
Information sourced from Uniprot.org