Anti-KLF5 antibody (1-250) (STJ24327)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal KLF5 (1-250) antibody for use in WB, IHC-P and ELISA in human and mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IHC-P/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:200-1:1000IHC-P:1:50-1:200ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.05% Proclin300, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | KLF5 |
| Gene ID | 688 |
| Uniprot ID | KLF5_HUMAN |
| Immunogen Region | 1-250 |
| Immunogen Sequence | MATRVLSMSARLGPVPQPPA PQDEPVFAQLKPVLGAANPA RDAALFPGEELKHAHHRPQA QPAPAQAPQPAQPPATGPRL PPEDLVQTRCEMEKYLTPQL PPVPIIPEHKKYRRDSASVV DQFFTDTEGLPYSINMNVFL PDITHLRTGLYKSQRPCVTH IKTEPVAIFSHQSETTAPPP APTQALPEFTSIFSSHQTAA PEVNNIFIKQELPTPDLHLS VPTQQGHLYQLLNTPDLDM |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 1-250 of human KLF5 (NP_001721.2). |
Additional Info
| Tissue Specificity | Expressed only in testis and placenta. |
| Post Translational Modifications | Ubiquitinated. Polyubiquitination involves WWP1 and leads to proteasomal degradation of this protein. Deubiquitinated by ATXN3L. |
| Function | Transcription factor that binds to GC box promoter elements. Activates the transcription of these genes. |
| Protein Name | Krueppel-Like Factor 5Basic Transcription Element-Binding Protein 2Bte-Binding Protein 2Colon Krueppel-Like FactorGc-Box-Binding Protein 2Intestinal-Enriched Krueppel-Like FactorTranscription Factor Bteb2 |
| Database Links | Reactome: R-HSA-381340Reactome: R-HSA-9616222 |
| Cellular Localisation | Nucleus |
| Alternative Antibody Names | Anti-Krueppel-Like Factor 5 antibodyAnti-Basic Transcription Element-Binding Protein 2 antibodyAnti-Bte-Binding Protein 2 antibodyAnti-Colon Krueppel-Like Factor antibodyAnti-Gc-Box-Binding Protein 2 antibodyAnti-Intestinal-Enriched Krueppel-Like Factor antibodyAnti-Transcription Factor Bteb2 antibodyAnti-KLF5 antibodyAnti-BTEB2 antibodyAnti-CKLF antibodyAnti-IKLF antibody |
Information sourced from Uniprot.org