Anti-KLF4/GKLF antibody (N-Term) (STJ70191)
SPECIFICATIONS
ClonalityPolyclonal
HostGoat
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Goat polyclonal antibody anti-KLF4/GKLF (N-Term) is suitable for use in ELISA and Western Blot research applications. |
| Applications | Pep-ELISA/WB |
| Host | Goat |
| Reactivity | Human/Mouse/Rat/Cow |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 0.5 mg/mL |
| Purification | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Dilution Range | Peptide ELISA: antibody detection limit dilution 1:64000.WB: Experiments gave strong bands at 75-90kDa and a faint 50-kDa band in Human Duodenal lysate after 0.1ยตg/ml antibody staining. These bands correspond to earlier findings in literature (P |
| Formulation | 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA |
| Storage Instruction | Store at-20ยฐC on receipt and minimise freeze-thaw cycles. |
Target Information
| Gene Symbol | KLF4 |
| Gene ID | 9314 |
| Uniprot ID | KLF4_HUMAN |
| Accession Number | NP_004226.2 |
| Immunogen Region | N-Term |
| Immunogen Sequence | AVSDALLPSFST |
Additional Info
| Function | Transcription factor.can act both as activator and as repressor. Binds the 5'-CACCC-3' core sequence. Binds to the promoter region of its own gene and can activate its own transcription. Regulates the expression of key transcription factors during embryonic development. Plays an important role in maintaining embryonic stem cells, and in preventing their differentiation. Required for establishing the barrier function of the skin and for postnatal maturation and maintenance of the ocular surface. Involved in the differentiation of epithelial cells and may also function in skeletal and kidney development. Contributes to the down-regulation of p53/TP53 transcription. |
| Protein Name | Krueppel-Like Factor 4Epithelial Zinc Finger Protein EzfGut-Enriched Krueppel-Like Factor |
| Database Links | Reactome: R-HSA-381340Reactome: R-HSA-422085Reactome: R-HSA-452723Reactome: R-HSA-9617828 |
| Cellular Localisation | NucleusCytoplasm |
| Alternative Antibody Names | Anti-Krueppel-Like Factor 4 antibodyAnti-Epithelial Zinc Finger Protein Ezf antibodyAnti-Gut-Enriched Krueppel-Like Factor antibodyAnti-KLF4 antibodyAnti-EZF antibodyAnti-GKLF antibody |
Information sourced from Uniprot.org