• Western blot analysis of extracts of various cell lines, using KLF11 antibody (STJ11100587) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 10s.

Anti-KLF11 antibody (13-107) (STJ11100587)

SKU:
STJ11100587

£112.50 - £522.50
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Host: Rabbit
Applications: WB
Reactivity: Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-KLF11 (13-107) is suitable for use in Western Blot research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3.
Purification: Affinity purification
Dilution Range: WB 1:500-1:2000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: KLF11
Gene ID: 8462
Uniprot ID: KLF11_HUMAN
Immunogen Region: 13-107
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 13-107 of human KLF11 (NP_003588.1).
Immunogen Sequence: RAVDIMDICESILERKRHDS ERSTCSILEQTDMEAVEALV CMSSWGQRSQKGDLLRIRPL TPVSDSGDVTTTVHMDAATP ELPKDFHSLSTLCIT
Tissue Specificity Ubiquitous. Higher expression in erythroid cells.
Function Transcription factor. Activates the epsilon- and gamma-globin gene promoters and, to a much lower degree, the beta-globin gene and represses promoters containing SP1-like binding inhibiting cell growth. Represses transcription of SMAD7 which enhances TGF-beta signaling. Induces apoptosis.
Protein Name Krueppel-Like Factor 11
Transforming Growth Factor-Beta-Inducible Early Growth Response Protein 2
Tgfb-Inducible Early Growth Response Protein 2
Tieg-2
Cellular Localisation Nucleus
Alternative Antibody Names Anti-Krueppel-Like Factor 11 antibody
Anti-Transforming Growth Factor-Beta-Inducible Early Growth Response Protein 2 antibody
Anti-Tgfb-Inducible Early Growth Response Protein 2 antibody
Anti-Tieg-2 antibody
Anti-KLF11 antibody
Anti-FKLF antibody
Anti-TIEG2 antibody

Information sourced from Uniprot.org

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