Anti-KLF10 antibody (228-278 aa) (STJ194316)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthesized peptide derived from the human KLF10 at the amino acid range 228-278
General Information
| Short Description | Rabbit polyclonal anti-Krueppel-like factor 10 (228-278 aa) for use in WB in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | KLF10 |
| Gene ID | 7071 |
| Uniprot ID | KLF10_HUMAN |
| Immunogen | Synthesized peptide derived from the human KLF10 at the amino acid range 228-278 |
| Immunogen Region | 228-278 aa |
| Specificity | This antibody detects endogenous levels of KLF10 at Human/Mouse/Rat |
Additional Info
| Function | Transcriptional repressor which binds to the consensus sequence 5'-GGTGTG-3'. Plays a role in the regulation of the circadian clock.binds to the GC box sequence in the promoter of the core clock component ARTNL/BMAL1 and represses its transcriptional activity. Regulates the circadian expression of genes involved in lipogenesis, gluconeogenesis, and glycolysis in the liver. Represses the expression of PCK2, a rate-limiting step enzyme of gluconeogenesis. May play a role in the cell cycle regulation. |
| Protein Name | Krueppel-Like Factor 10Egr-AlphaTransforming Growth Factor-Beta-Inducible Early Growth Response Protein 1Tgfb-Inducible Early Growth Response Protein 1Tieg-1 |
| Database Links | |
| Cellular Localisation | Nucleus |
| Alternative Antibody Names | Anti-Krueppel-Like Factor 10 antibodyAnti-Egr-Alpha antibodyAnti-Transforming Growth Factor-Beta-Inducible Early Growth Response Protein 1 antibodyAnti-Tgfb-Inducible Early Growth Response Protein 1 antibodyAnti-Tieg-1 antibodyAnti-KLF10 antibodyAnti-TIEG antibodyAnti-TIEG1 antibody |
Information sourced from Uniprot.org