| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:2000 ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | KLC3 |
| Gene ID: | 147700 |
| Uniprot ID: | KLC3_HUMAN |
| Immunogen Region: | 1-135 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-135 of human KLC3 (NP_803136.2). |
| Immunogen Sequence: | MSVQVAAPGSAGLGPERLSP EELVRQTRQVVQGLEALRAE HHGLAGHLAEALAGQGPAAG LEMLEEKQQVVSHSLEAIEL GLGEAQVLLALSAHVGALEA EKQRLRSQARRLAQENVWLR EELEETQRRLRASEE |
| Function | Kinesin is a microtubule-associated force-producing protein that may play a role in organelle transport. Plays a role during spermiogenesis in the development of the sperm tail midpiece and in the normal function of spermatozoa. May play a role in the formation of the mitochondrial sheath formation in the developing spermatid midpiece. |
| Protein Name | Kinesin Light Chain 3 Klc2-Like Kinesin Light Chain 2 |
| Database Links | Reactome: R-HSA-2132295 Reactome: R-HSA-5625970 Reactome: R-HSA-6811434 Reactome: R-HSA-983189 |
| Cellular Localisation | Cytoplasm Cytoskeleton Mitochondrion In Elongating Spermatid Tail Midpiece Localized In Outer Dense Fibers (Odfs) And Associates With Mitochondria Also Localizes To The Manchette In Elongating Spermatids |
| Alternative Antibody Names | Anti-Kinesin Light Chain 3 antibody Anti-Klc2-Like antibody Anti-Kinesin Light Chain 2 antibody Anti-KLC3 antibody Anti-KLC2 antibody Anti-KLC2L antibody |
Information sourced from Uniprot.org