Anti-KIZ antibody (320-400 aa) (STJ190134)

SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthesized peptide derived from the human protein at the amino acid range 320-400
STJ190134
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General Information

Short DescriptionRabbit polyclonal anti-Centrosomal protein kizuna (320-400 aa) for use in WB and ELISA in Human, Rat and Mouse samples. Datasheet included with dilution recommendations, and related reagents.
ApplicationsWB/ELISA
HostRabbit
ReactivityHuman/Rat/Mouse
NoteSTRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Product Properties

ClonalityPolyclonal
IsotypeIgG
ConjugationUnconjugated
Concentration1 mg/mL
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Dilution RangeWB 1:500-2000
ELISA 1:5000-20000
FormulationLiquid in PBS containing 50% Glycerol and 0.02% Sodium Azide.
Storage InstructionStore at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.

Target Information

Gene SymbolKIZ
Gene ID55857
Uniprot IDKIZ_HUMAN
ImmunogenSynthesized peptide derived from the human protein at the amino acid range 320-400
Immunogen Region320-400 aa
SpecificityKIZ Polyclonal Antibody detects endogenous levels of protein.

Additional Info

Function Centrosomal protein required for establishing a robust mitotic centrosome architecture that can endure the forces that converge on the centrosomes during spindle formation. Required for stabilizing the expanded pericentriolar material around the centriole.
Protein Name Centrosomal Protein Kizuna
Polo-Like Kinase 1 Substrate 1
Database Links
Cellular Localisation Cytoplasm
Cytoskeleton
Microtubule Organizing Center
Centrosome
Cilium Basal Body
Localizes To Centrosomes Throughout The Cell Cycle
After Centrosome Duplication
It Usually Remains Associated Only With The Mother Centrosome
Containing The Older Mature Centriole And Particles Surrounding It
During Prophase
Additional Particles Accumulate Around Both Separating Centrosomes
Does Not Accumulate At The Microtubule Minus Ends
But Instead Localizes To The Centrosomes And Centrosome-Surrounding Area In A Microtubule-Independent And Dependent Manner
Respectively
Alternative Antibody Names Anti-Centrosomal Protein Kizuna antibody
Anti-Polo-Like Kinase 1 Substrate 1 antibody
Anti-KIZ antibody
Anti-C20orf19 antibody
Anti-NCRNA00153 antibody
Anti-PLK1S1 antibody
Anti-HT013 antibody

Information sourced from Uniprot.org

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