Anti-KIRREL3/NEPH2 antibody [N321C/49R] (STJA0019224)
SPECIFICATIONS
ClonalityMonoclonal
HostMouse
ConjugationUnconjugated
IsotypeIgG2a
General Information
| Short Description | Mouse monoclonal KIRREL3/NEPH2 antibody for use in IF, IHC and WB in mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | IF/IHC/WB |
| Host | Mouse |
| Reactivity | Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO) MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS |
Product Properties
| Clonality | Monoclonal |
| Clone ID | N321C/49R |
| Isotype | IgG2a |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | Protein A/G purified from cell culture supernatant |
| Formulation | 0.01M PBS, pH 7.4. |
| Storage Instruction | Suitable for storage at +4°C between 1-2 weeks For longer term store at-20°C for up to 12 months |
Target Information
| Gene Symbol | Kirrel3 |
| Gene ID | 67703 |
| Uniprot ID | KIRR3_MOUSE |
Additional Info
| Post Translational Modifications | Undergoes proteolysis by a metalloprotease and gives rise to a soluble form. |
| Function | Synaptic adhesion molecule required for the formation of target-specific synapses. Required for formation of target-specific synapses at hippocampal mossy fiber synapses. Required for formation of mossy fiber filopodia, the synaptic structures connecting dentate granule and GABA neurons. Probably acts as a homophilic adhesion molecule that promotes trans-cellular interactions and stabilize mossy fiber filipodia contact and subsequent synapse formation. Required for the coalescence of vomeronasal sensory neuron axons. May be involved in the hematopoietic supportive capacity of stroma cells.the secreted extracellular domain is directly responsible for supporting hematopoietic stem cells. |
| Protein Name | Kin Of Irre-Like Protein 3Kin Of Irregular Chiasm-Like Protein 3Nephrin-Like Protein 2Mkirre Cleaved Into - Processed Kin Of Irre-Like Protein 3 |
| Database Links | Reactome: R-MMU-373753 |
| Cellular Localisation | Cell MembraneSingle-Pass Type I Membrane ProteinCell ProjectionAxonDendriteProcessed Kin Of Irre-Like Protein 3: Secreted |
| Alternative Antibody Names | Anti-Kin Of Irre-Like Protein 3 antibodyAnti-Kin Of Irregular Chiasm-Like Protein 3 antibodyAnti-Nephrin-Like Protein 2 antibodyAnti-Mkirre Cleaved Into - Processed Kin Of Irre-Like Protein 3 antibodyAnti-Kirrel3 antibodyAnti-Kiaa1867 antibodyAnti-Neph2 antibody |
Information sourced from Uniprot.org