Anti-KIR3DL2 antibody (221-270 aa) (STJ98750)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthetic peptide from the human protein at the amino acid range 221-270
General Information
| Short Description | Rabbit polyclonal anti-Killer cell immunoglobulin-like receptor 3DL2 (221-270 aa) for use in IHC, IF and ELISA in Human, Rat and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | IHC/IF/ELISA |
| Host | Rabbit |
| Reactivity | Human/Rat/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | IHC-P 1:50-200ELISA 1:10000-20000IF 1:50-200 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20ยฐC for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | KIR3DL2 |
| Gene ID | 3812 |
| Uniprot ID | KI3L2_HUMAN |
| Immunogen | Synthetic peptide from the human protein at the amino acid range 221-270 |
| Immunogen Region | 221-270 aa |
| Specificity | The antibody detects endogenous CD158k |
Additional Info
| Function | Receptor on natural killer (NK) cells and T cells for MHC class I molecules. Upon binding of peptide-free HLA-F open conformer, negatively regulates NK and T cell effector functions. Acts as a receptor on astrocytes for HLA-F. Through interaction with HLA-F, may protect motor neurons from astrocyte-induced toxicity. |
| Protein Name | Killer Cell Immunoglobulin-Like Receptor 3dl2Cd158 Antigen-Like Family Member KNatural Killer-Associated Transcript 4Nkat-4P70 Natural Killer Cell Receptor Clone Cl-5P70 Nk Receptor Cl-5Cd Antigen Cd158k |
| Database Links | Reactome: R-HSA-198933 |
| Cellular Localisation | Cell MembraneSingle-Pass Type I Membrane Protein |
| Alternative Antibody Names | Anti-Killer Cell Immunoglobulin-Like Receptor 3dl2 antibodyAnti-Cd158 Antigen-Like Family Member K antibodyAnti-Natural Killer-Associated Transcript 4 antibodyAnti-Nkat-4 antibodyAnti-P70 Natural Killer Cell Receptor Clone Cl-5 antibodyAnti-P70 Nk Receptor Cl-5 antibodyAnti-Cd Antigen Cd158k antibodyAnti-KIR3DL2 antibodyAnti-CD158K antibodyAnti-NKAT4 antibody |
Information sourced from Uniprot.org