Anti-KIR3DL1 antibody (22-222) (STJ24317)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal KIR3DL1 (22-222) antibody for use in WB and ELISA in human and mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | KIR3DL1 |
| Gene ID | 3811 |
| Uniprot ID | KI3L1_HUMAN |
| Immunogen Region | 22-222 |
| Immunogen Sequence | HMGGQDKPFLSAWPSAVVPR GGHVTLRCHYRHRFNNFMLY KEDRIHIPIFHGRIFQESFN MSPVTTAHAGNYTCRGSHPH SPTGWSAPSNPVVIMVTGNH RKPSLLAHPGPLVKSGERVI LQCWSDIMFEHFFLHKEGIS KDPSRLVGQIHDGVSKANFS IGPMMLALAGTYRCYGSVTH TPYQLSAPSDPLDIVVTGPY E |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 22-222 of human KIR3DL1 (NP_037421.2). |
Additional Info
| Function | Receptor on natural killer (NK) cells for HLA Bw4 allele. Inhibits the activity of NK cells thus preventing cell lysis. |
| Protein Name | Killer Cell Immunoglobulin-Like Receptor 3dl1Cd158 Antigen-Like Family Member EHla-Bw4-Specific Inhibitory Nk Cell ReceptorNatural Killer-Associated Transcript 3Nkat-3P70 Natural Killer Cell Receptor Clones Cl-2/Cl-11P70 Nk Receptor Cl-2/Cl-11Cd Antigen Cd158e |
| Database Links | Reactome: R-HSA-198933 |
| Cellular Localisation | Cell MembraneSingle-Pass Type I Membrane Protein |
| Alternative Antibody Names | Anti-Killer Cell Immunoglobulin-Like Receptor 3dl1 antibodyAnti-Cd158 Antigen-Like Family Member E antibodyAnti-Hla-Bw4-Specific Inhibitory Nk Cell Receptor antibodyAnti-Natural Killer-Associated Transcript 3 antibodyAnti-Nkat-3 antibodyAnti-P70 Natural Killer Cell Receptor Clones Cl-2/Cl-11 antibodyAnti-P70 Nk Receptor Cl-2/Cl-11 antibodyAnti-Cd Antigen Cd158e antibodyAnti-KIR3DL1 antibodyAnti-CD158E antibodyAnti-NKAT3 antibodyAnti-NKB1 antibody |
Information sourced from Uniprot.org