| Post Translational Modifications | N-glycosylated, glycosylation varies depending on the allele which alters cell surface expression levels. |
| Function | Activating natural killer (NK) receptor that recognizes C2 epitopes of HLA-C alleles. Bridging the innate and adaptive immune systems, NK cells express a number of cell surface receptors which either inhibit or stimulate their cytotoxicity. Able to activate NK cells citotoxicity and cytokine production such as IFNG. Receptor functions are attenuated even lost in some alleles, such as KIR2DS5*002 represented in this entry. |
| Protein Name | Killer Cell Immunoglobulin-Like Receptor 2ds5Cd158 Antigen-Like Family Member GNatural Killer-Associated Transcript 9Nkat-9Cd Antigen Cd158g |
| Database Links | Reactome: R-HSA-2172127 |
| Cellular Localisation | Cell MembraneSingle-Pass Type I Membrane ProteinExtracellular Side |
| Alternative Antibody Names | Anti-Killer Cell Immunoglobulin-Like Receptor 2ds5 antibodyAnti-Cd158 Antigen-Like Family Member G antibodyAnti-Natural Killer-Associated Transcript 9 antibodyAnti-Nkat-9 antibodyAnti-Cd Antigen Cd158g antibodyAnti-KIR2DS5 antibodyAnti-CD158G antibodyAnti-NKAT9 antibody |
Information sourced from Uniprot.org
