| Host: |
Rabbit |
| Applications: |
WB/IF |
| Reactivity: |
Human/Mouse |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-KIR2DL3 (22-245) is suitable for use in Western Blot and Immunofluorescence research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:500-1:2000IF/ICC 1:50-1:200 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
KIR2DL3 |
| Gene ID: |
3804 |
| Uniprot ID: |
KI2L3_HUMAN |
| Immunogen Region: |
22-245 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 22-245 of human KIR2DL3 (NP_056952.2). |
| Immunogen Sequence: |
HEGVHRKPSLLAHPGPLVKS EETVILQCWSDVRFQHFLLH REGKFKDTLHLIGEHHDGVS KANFSIGPMMQDLAGTYRCY GSVTHSPYQLSAPSDPLDIV ITGLYEKPSLSAQPGPTVLA GESVTLSCSSRSSYDMYHLS REGEAHERRFSAGPKVNGTF QADFPLGPATHGGTYRCFGS FRDSPYEWSNSSDPLLVSVT GNPSNSWPSPTEPSSETGNP RHLH |
| Function | Receptor on natural killer (NK) cells for HLA-C alleles (HLA-Cw1, HLA-Cw3 and HLA-Cw7). Inhibits the activity of NK cells thus preventing cell lysis. |
| Protein Name | Killer Cell Immunoglobulin-Like Receptor 2dl3Cd158 Antigen-Like Family Member B2Kir-023gbKiller Inhibitory Receptor Cl 2-3Nkat2aNkat2bNatural Killer-Associated Transcript 2Nkat-2P58 Natural Killer Cell Receptor Clone Cl-6P58 Nk Receptor Cl-6P58.2 Mhc Class-I-Specific Nk ReceptorCd Antigen Cd158b2 |
| Database Links | Reactome: R-HSA-198933 |
| Cellular Localisation | Cell MembraneSingle-Pass Type I Membrane Protein |
| Alternative Antibody Names | Anti-Killer Cell Immunoglobulin-Like Receptor 2dl3 antibodyAnti-Cd158 Antigen-Like Family Member B2 antibodyAnti-Kir-023gb antibodyAnti-Killer Inhibitory Receptor Cl 2-3 antibodyAnti-Nkat2a antibodyAnti-Nkat2b antibodyAnti-Natural Killer-Associated Transcript 2 antibodyAnti-Nkat-2 antibodyAnti-P58 Natural Killer Cell Receptor Clone Cl-6 antibodyAnti-P58 Nk Receptor Cl-6 antibodyAnti-P58.2 Mhc Class-I-Specific Nk Receptor antibodyAnti-Cd Antigen Cd158b2 antibodyAnti-KIR2DL3 antibodyAnti-CD158B2 antibodyAnti-KIRCL23 antibodyAnti-NKAT2 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
