Immunofluorescence analysis of HepG2 cells using KIR2DL3 antibody (STJ24316). Blue: DAPI for nuclear staining.

Anti-KIR2DL3 antibody (22-245) (STJ24316)

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STJ24316
£112.50 - £524.50
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Covered by St John's Laboratory Guarantee

Host: Rabbit
Applications: WB/IF/ICC/ELISA
Reactivity: Human/Mouse
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Clonality : Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3.
Purification: Affinity purification
Concentration: Lot specific
Dilution Range: WB:1:500-1:2000
IF/ICC:1:50-1:200
ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements.
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: KIR2DL3
Gene ID: 3804
Uniprot ID: KI2L3_HUMAN
Immunogen Region: 22-245
Specificity: Recombinant fusion protein containing a sequence corresponding to amino acids 22-245 of human KIR2DL3 (NP_056952.2).
Immunogen Sequence: HEGVHRKPSLLAHPGPLVKS EETVILQCWSDVRFQHFLLH REGKFKDTLHLIGEHHDGVS KANFSIGPMMQDLAGTYRCY GSVTHSPYQLSAPSDPLDIV ITGLYEKPSLSAQPGPTVLA GESVTLSCSSRSSYDMYHLS REGEAHERRFSAGPKVNGTF QADFPLGPATHGGTYRCFGS FRDSPYEWSNSSDPLLVSVT GNPSNSWPSPTEPSSETGNP RHLH
Function Receptor on natural killer (NK) cells for HLA-C alleles (HLA-Cw1, HLA-Cw3 and HLA-Cw7). Inhibits the activity of NK cells thus preventing cell lysis.
Protein Name Killer Cell Immunoglobulin-Like Receptor 2dl3
Cd158 Antigen-Like Family Member B2
Kir-023gb
Killer Inhibitory Receptor Cl 2-3
Nkat2a
Nkat2b
Natural Killer-Associated Transcript 2
Nkat-2
P58 Natural Killer Cell Receptor Clone Cl-6
P58 Nk Receptor Cl-6
P58.2 Mhc Class-I-Specific Nk Receptor
Cd Antigen Cd158b2
Database Links Reactome: R-HSA-198933
Cellular Localisation Cell Membrane
Single-Pass Type I Membrane Protein
Alternative Antibody Names Anti-Killer Cell Immunoglobulin-Like Receptor 2dl3 antibody
Anti-Cd158 Antigen-Like Family Member B2 antibody
Anti-Kir-023gb antibody
Anti-Killer Inhibitory Receptor Cl 2-3 antibody
Anti-Nkat2a antibody
Anti-Nkat2b antibody
Anti-Natural Killer-Associated Transcript 2 antibody
Anti-Nkat-2 antibody
Anti-P58 Natural Killer Cell Receptor Clone Cl-6 antibody
Anti-P58 Nk Receptor Cl-6 antibody
Anti-P58.2 Mhc Class-I-Specific Nk Receptor antibody
Anti-Cd Antigen Cd158b2 antibody
Anti-KIR2DL3 antibody
Anti-CD158B2 antibody
Anti-KIRCL23 antibody
Anti-NKAT2 antibody

Information sourced from Uniprot.org

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