Anti-KIN antibody (STJA0008645)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthesized peptide derived from human KIN17
General Information
| Short Description | Rabbit polyclonal anti-DNA/RNA-binding protein KIN17 for use in WB in Human and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB |
| Host | Rabbit |
| Reactivity | Human/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | KIN |
| Gene ID | 22944 |
| Uniprot ID | KIN17_HUMAN |
| Immunogen | Synthesized peptide derived from human KIN17 |
| Specificity | This antibody detects endogenous levels of KIN17 at Human, Mouse |
Additional Info
| Function | Involved in DNA replication and the cellular response to DNA damage. May participate in DNA replication factories and create a bridge between DNA replication and repair mediated by high molecular weight complexes. May play a role in illegitimate recombination and regulation of gene expression. May participate in mRNA processing. Binds, in vitro, to double-stranded DNA. Also shown to bind preferentially to curved DNA in vitro and in vivo. Binds via its C-terminal domain to RNA in vitro. |
| Protein Name | Dna/Rna-Binding Protein Kin17Binding To Curved DnaKin - Antigenic Determinant Of Reca Protein Homolog |
| Database Links | Reactome: R-HSA-8876725 |
| Cellular Localisation | NucleusCytoplasmDuring S PhaseStrongly Associated With The Nuclear MatrixAnd To Chromosomal Dna In The Presence Of Dna DamageAlso Shows Cytoplasmic Localization In Elongated Spermatids |
| Alternative Antibody Names | Anti-Dna/Rna-Binding Protein Kin17 antibodyAnti-Binding To Curved Dna antibodyAnti-Kin - Antigenic Determinant Of Reca Protein Homolog antibodyAnti-KIN antibodyAnti-BTCD antibodyAnti-KIN17 antibody |
Information sourced from Uniprot.org