Anti-KIFAP3 antibody [R03-5E9] (STJA0037324)
SPECIFICATIONS
ClonalityMonoclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenA synthesized peptide derived from human KIFAP3
General Information
| Short Description | Rabbit monoclonal anti-KIFAP3 for use in WB, IHC-P, ICC, IF and FC in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IHC-P/ICC/IF/FC |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | R03-5E9 |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Purification | Affinity Purified |
| Dilution Range | WB 1:500-1:1000IHC 1:50-1:100IF 1:50-1:200FC 1:50-1:100 |
| Formulation | Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Storage Instruction | Store at 4°C short term. Aliquot and store at-20°C long term. Avoid freeze/thaw cycles. |
Target Information
| Gene Symbol | KIFAP3 |
| Gene ID | 22920 |
| Uniprot ID | KIFA3_HUMAN |
| Immunogen | A synthesized peptide derived from human KIFAP3 |
Additional Info
| Post Translational Modifications | Phosphorylated on tyrosine residues by SRC in vitro.this reduces the binding affinity of the protein for RAP1GDS1. |
| Function | Involved in tethering the chromosomes to the spindle pole and in chromosome movement. Binds to the tail domain of the KIF3A/KIF3B heterodimer to form a heterotrimeric KIF3 complex and may regulate the membrane binding of this complex. |
| Protein Name | Kinesin-Associated Protein 3Kap-3Kap3Smg Gds-Associated Protein |
| Database Links | Reactome: R-HSA-1445148Reactome: R-HSA-2132295Reactome: R-HSA-5620924Reactome: R-HSA-6811434Reactome: R-HSA-983189 |
| Cellular Localisation | |
| Alternative Antibody Names | Anti-Kinesin-Associated Protein 3 antibodyAnti-Kap-3 antibodyAnti-Kap3 antibodyAnti-Smg Gds-Associated Protein antibodyAnti-KIFAP3 antibodyAnti-KIF3AP antibodyAnti-SMAP antibody |
Information sourced from Uniprot.org