Anti-KIF3A antibody [R03-8K9] (STJA0036508)
SPECIFICATIONS
ClonalityMonoclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenA synthesized peptide derived from human KIF3A
General Information
| Short Description | Rabbit monoclonal anti-KIF3A for use in WB and IP in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IP |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | R03-8K9 |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Purification | Affinity Chromatography |
| Dilution Range | WB 1:500-1:1000IP 1:50 |
| Formulation | Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Storage Instruction | Store at 4°C short term. Aliquot and store at-20°C long term. Avoid freeze/thaw cycles. |
Target Information
| Gene Symbol | KIF3A |
| Gene ID | 11127 |
| Uniprot ID | KIF3A_HUMAN |
| Immunogen | A synthesized peptide derived from human KIF3A |
Additional Info
| Function | Microtubule-based anterograde translocator for membranous organelles. Plus end-directed microtubule sliding activity in vitro. Plays a role in primary cilia formation. Plays a role in centriole cohesion and subdistal appendage organization and function. Regulates the formation of the subdistal appendage via recruitment of DCTN1 to the centriole. Also required for ciliary basal feet formation and microtubule anchoring to mother centriole. |
| Protein Name | Kinesin-Like Protein Kif3aMicrotubule Plus End-Directed Kinesin Motor 3a |
| Database Links | Reactome: R-HSA-1445148Reactome: R-HSA-2132295Reactome: R-HSA-5610787Reactome: R-HSA-5620924Reactome: R-HSA-5635838Reactome: R-HSA-6811434Reactome: R-HSA-983189 |
| Cellular Localisation | CytoplasmCytoskeletonCell ProjectionCiliumMicrotubule Organizing CenterCentrosomeCentrioleLocalizes To The Subdistal Appendage Region Of The Centriole |
| Alternative Antibody Names | Anti-Kinesin-Like Protein Kif3a antibodyAnti-Microtubule Plus End-Directed Kinesin Motor 3a antibodyAnti-KIF3A antibodyAnti-KIF3 antibody |
Information sourced from Uniprot.org