| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human/Mouse/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-KIF20A (591-890) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:200-1:2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
KIF20A |
| Gene ID: |
10112 |
| Uniprot ID: |
KI20A_HUMAN |
| Immunogen Region: |
591-890 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 591-890 of human KIF20A (NP_005724.1). |
| Immunogen Sequence: |
EICNEMVEQMQQREQWCSEH LDTQKELLEEMYEEKLNILK ESLTSFYQEEIQERDEKIEE LEALLQEARQQSVAHQQSGS ELALRRSQRLAASASTQQLQ EVKAKLQQCKAELNSTTEEL HKYQKMLEPPPSAKPFTIDV DKKLEEGQKNIRLLRTELQK LGESLQSAERACCHSTGAGK LRQALTTCDDILIKQDQTLA ELQNNMVLVKLDLRKKAACI AEQYHTVLKLQGQVSAKKR |
| Post Translational Modifications | Phosphorylated by PLK1 at Ser-528 during mitosis, creating a docking site for PLK1 and recruiting PLK1 at central spindle. |
| Function | Mitotic kinesin required for chromosome passenger complex (CPC)-mediated cytokinesis. Following phosphorylation by PLK1, involved in recruitment of PLK1 to the central spindle. Interacts with guanosine triphosphate (GTP)-bound forms of RAB6A and RAB6B. May act as a motor required for the retrograde RAB6 regulated transport of Golgi membranes and associated vesicles along microtubules. Has a microtubule plus end-directed motility. |
| Protein Name | Kinesin-Like Protein Kif20aGg10_2Mitotic Kinesin-Like Protein 2Mklp2Rab6-Interacting Kinesin-Like ProteinRabkinesin-6 |
| Database Links | Reactome: R-HSA-2132295Reactome: R-HSA-6811434Reactome: R-HSA-68884Reactome: R-HSA-983189 |
| Cellular Localisation | Golgi ApparatusCytoplasmCytoskeletonSpindleLocalizes To The Spindle Midzone During Anaphase And Telophase |
| Alternative Antibody Names | Anti-Kinesin-Like Protein Kif20a antibodyAnti-Gg10_2 antibodyAnti-Mitotic Kinesin-Like Protein 2 antibodyAnti-Mklp2 antibodyAnti-Rab6-Interacting Kinesin-Like Protein antibodyAnti-Rabkinesin-6 antibodyAnti-KIF20A antibodyAnti-MKLP2 antibodyAnti-RAB6KIFL antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
