| Host: | Rabbit |
| Applications: | WB |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Rabbit polyclonal antibody anti-Kinesin-like protein KIF1B (1331-1381 aa) is suitable for use in Western Blot research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: | 1 mg/mL |
| Dilution Range: | WB 1:500-2000 |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | KIF1B |
| Gene ID: | 23095 |
| Uniprot ID: | KIF1B_HUMAN |
| Immunogen Region: | 1331-1381 aa |
| Specificity: | This antibody detects endogenous levels of KIF1B at Human/Mouse/Rat |
| Immunogen: | Synthesized peptide derived from the human KIF1B at the amino acid range 1331-1381 |
| Function | Has a plus-end-directed microtubule motor activity and functions as a motor for transport of vesicles and organelles along microtubules. Isoform 2: Has a plus-end-directed microtubule motor activity and functions as a motor for anterograde synaptic vesicle transport along axonal microtubules from the cell body to the presynapse in neuronal cells. Functions as a downstream effector in a developmental apoptotic pathway that is activated when nerve growth factor (NGF) becomes limiting for neuronal progenitor cells. Isoform 3: Has a plus-end-directed microtubule motor activity and functions as a motor for anterograde transport of mitochondria. |
| Protein Name | Kinesin-Like Protein Kif1b Klp |
| Database Links | Reactome: R-HSA-6811434 Reactome: R-HSA-983189 |
| Cellular Localisation | Cytoplasm Cytoskeleton Has A Plus-End-Directed Microtubule Motor Activity And Therefore Associates With Microtubules Isoform 2: Cytoplasmic Vesicle Secretory Vesicle Synaptic Vesicle Membrane Associates With Synaptic Vesicles And Mediates Their Anterograde Transport Along Axonal Microtubules Isoform 3: Mitochondrion Associates With Mitochondria And Mediates Their Movement Along Microtubules |
| Alternative Antibody Names | Anti-Kinesin-Like Protein Kif1b antibody Anti-Klp antibody Anti-KIF1B antibody Anti-KIAA0591 antibody Anti-KIAA1448 antibody |
Information sourced from Uniprot.org