| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit monoclonal antibody anti-Eg5 (900-1056) is suitable for use in Western Blot research applications. |
| Clonality: |
Monoclonal |
| Clone ID: |
S6MR |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.02% Sodium Azide, 0.05% BSA, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:500-1:2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
KIF11 |
| Gene ID: |
3832 |
| Uniprot ID: |
KIF11_HUMAN |
| Immunogen Region: |
900-1056 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 900-1056 of human EG5/KIF11 (P52732). |
| Immunogen Sequence: |
ETIKIGLTKLNCFLEQDLKL DIPTGTTPQRKSYLYPSTLV RTEPREHLLDQLKRKQPELL MMLNCSENNKEETIPDVDVE EAVLGQYTEEPLSQEPSVDA GVDCSSIGGVPFFQHKKSHG KDKENRGINTLERSKVEETT EHLVTKSRLPLRAQINL |
| Post Translational Modifications | Phosphorylated exclusively on serine during S phase, but on both serine and Thr-926 during mitosis, so controlling the association of KIF11 with the spindle apparatus (probably during early prophase). A subset of this protein primarily localized at the spindle pole is phosphorylated by NEK6 during mitosis.phosphorylation is required for mitotic function. |
| Function | Motor protein required for establishing a bipolar spindle during mitosis. Required in non-mitotic cells for transport of secretory proteins from the Golgi complex to the cell surface. |
| Protein Name | Kinesin-Like Protein Kif11Kinesin-Like Protein 1Kinesin-Like Spindle Protein HkspKinesin-Related Motor Protein Eg5Thyroid Receptor-Interacting Protein 5Tr-Interacting Protein 5Trip-5 |
| Database Links | Reactome: R-HSA-2132295Reactome: R-HSA-6811434Reactome: R-HSA-983189 |
| Cellular Localisation | CytoplasmCytoskeletonSpindle Pole |
| Alternative Antibody Names | Anti-Kinesin-Like Protein Kif11 antibodyAnti-Kinesin-Like Protein 1 antibodyAnti-Kinesin-Like Spindle Protein Hksp antibodyAnti-Kinesin-Related Motor Protein Eg5 antibodyAnti-Thyroid Receptor-Interacting Protein 5 antibodyAnti-Tr-Interacting Protein 5 antibodyAnti-Trip-5 antibodyAnti-KIF11 antibodyAnti-EG5 antibodyAnti-KNSL1 antibodyAnti-TRIP5 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
