Anti-KIAA0319 antibody (Internal) (STJ70837)
SPECIFICATIONS
ClonalityPolyclonal
HostGoat
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Goat polyclonal antibody anti-KIAA0319 (Internal) is suitable for use in ELISA and Immunohistochemistry research applications. |
| Applications | Pep-ELISA/IHC |
| Host | Goat |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 0.5 mg/mL |
| Purification | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Dilution Range | Peptide ELISA: antibody detection limit dilution 1:64000.WB: Preliminary experiments gave an approx 35kDa band in Human Brain lysates after 1ยตg/ml antibody staining. Please note that currently we cannot find an explanation in the literature for |
| Formulation | 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA |
| Storage Instruction | Store at-20ยฐC on receipt and minimise freeze-thaw cycles. |
Target Information
| Gene Symbol | KIAA0319 |
| Gene ID | 9856 |
| Uniprot ID | K0319_HUMAN |
| Accession Number | NP_055624.2 |
| Immunogen Region | Internal |
| Immunogen Sequence | QLTEQRKDTLVRQ |
Additional Info
| Post Translational Modifications | N-glycosylated. O-glycosylated. Shedding of the extracellular domain and intramembrane cleavage produce several proteolytic products. The intramembrane cleavage releases a soluble cytoplasmic polypeptide that translocates to the nucleolus. |
| Function | Involved in neuronal migration during development of the cerebral neocortex. May function in a cell autonomous and a non-cell autonomous manner and play a role in appropriate adhesion between migrating neurons and radial glial fibers. May also regulate growth and differentiation of dendrites. |
| Protein Name | Dyslexia-Associated Protein Kiaa0319 |
| Database Links | Reactome: R-HSA-8856825Reactome: R-HSA-8856828 |
| Cellular Localisation | Cell MembraneSingle-Pass Type I Membrane ProteinEarly Endosome MembraneLow-Abundance Isoforms Lacking The Transmembrane Domain Have Been DescribedThese Are Secreted |
| Alternative Antibody Names | Anti-Dyslexia-Associated Protein Kiaa0319 antibodyAnti-KIAA0319 antibody |
Information sourced from Uniprot.org