Anti-Keratin 8 antibody [C51] (STJA0018397)
SPECIFICATIONS
ClonalityMonoclonal
HostMouse
ConjugationUnconjugated
General Information
| Short Description | Mouse monoclonal anti-Keratin-Type Ii Cytoskeletal 8 for use in IHC in Human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | IHC |
| Host | Mouse |
| Reactivity | Human |
| Note | FOR RESEARCH USE ONLY (RUO). |
Product Properties
| Clonality | Monoclonal |
| Clone ID | C51 |
| Conjugation | Unconjugated |
| Dilution Range | Please carry out application specific titration to determine the most appropriate dilution ratio. |
| Formulation | Cell culture supernatant with 0.09% Sodium azide, and Fetal Calf Serum |
| Storage Instruction | Shipped on gel ice packs. Store at 2-8C on arrival. |
Target Information
| Gene Symbol | KRT8 |
| Gene ID | 3856 |
| Uniprot ID | K2C8_HUMAN |
Additional Info
| Post Translational Modifications | Phosphorylation on serine residues is enhanced during EGF stimulation and mitosis. Ser-74 phosphorylation plays an important role in keratin filament reorganization. O-glycosylated. O-GlcNAcylation at multiple sites increases solubility, and decreases stability by inducing proteasomal degradation. O-glycosylated (O-GlcNAcylated), in a cell cycle-dependent manner. |
| Function | Together with KRT19, helps to link the contractile apparatus to dystrophin at the costameres of striated muscle. |
| Protein Name | Keratin - Type Ii Cytoskeletal 8Cytokeratin-8Ck-8Keratin-8K8Type-Ii Keratin Kb8 |
| Database Links | Reactome: R-HSA-6805567Reactome: R-HSA-6809371 |
| Cellular Localisation | CytoplasmNucleusNucleoplasmNucleus Matrix |
| Alternative Antibody Names | Anti-Keratin - Type Ii Cytoskeletal 8 antibodyAnti-Cytokeratin-8 antibodyAnti-Ck-8 antibodyAnti-Keratin-8 antibodyAnti-K8 antibodyAnti-Type-Ii Keratin Kb8 antibodyAnti-KRT8 antibodyAnti-CYK8 antibody |
Information sourced from Uniprot.org