• Anti-Keratin 19 antibody [EBS-IF-007] (STJ16101025)

Anti-Keratin 19 antibody [EBS-IF-007] (STJ16101025)

SKU:
STJ16101025

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Host: Mouse
Applications: FC/WB/IF/IHC
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Mouse monoclonal antibody anti-Keratin 19 is suitable for use in Flow Cytometry, Western Blot, Immunofluorescence and Immunohistochemistry research applications.
Clonality: Monoclonal
Clone ID: EBS-IF-007
Conjugation: Unconjugated
Isotype: IgG2ak
Formulation: PBS with 0.02% Sodium Azide.
Purification: Affinity purified from tissue culture.
Concentration: Can be provided as 100 µg/mL, 500 µg/mL or 1mg/mL.
Dilution Range: Flow Cytometry (1-2 µg/million cells in 0.1 ml, fix cells in 4% PFA for 10 min, at 4°C, permeabilize with 0, 2% saponin or digitonin for 15 min, at 4°C). Immunoblotting (1-2 µg/ml). Immunofluorescence (1-2 µg/ml). Immunohistology (formalin-fixed: 2-4
Storage Instruction: Store for up to 1 year at 2-8°C upon receipt.
Gene Symbol: KRT19
Gene ID: 3880
Uniprot ID: K1C19_HUMAN
Immunogen: A BALB/c mouse was immunized with human breast cancer cell line MCF-7. Fusion Partner: P3-X63-Ag8.653.
Tissue Specificity Expressed in a defined zone of basal keratinocytes in the deep outer root sheath of hair follicles. Also observed in sweat gland and mammary gland ductal and secretory cells, bile ducts, gastrointestinal tract, bladder urothelium, oral epithelia, esophagus, ectocervical epithelium (at protein level). Expressed in epidermal basal cells, in nipple epidermis and a defined region of the hair follicle. Also seen in a subset of vascular wall cells in both the veins and artery of human umbilical cord, and in umbilical cord vascular smooth muscle. Observed in muscle fibers accumulating in the costameres of myoplasm at the sarcolemma in structures that contain dystrophin and spectrin.
Function Involved in the organization of myofibers. Together with KRT8, helps to link the contractile apparatus to dystrophin at the costameres of striated muscle.
Protein Name Keratin - Type I Cytoskeletal 19
Cytokeratin-19
Ck-19
Keratin-19
K19
Database Links Reactome: R-HSA-6805567
Reactome: R-HSA-6809371
Alternative Antibody Names Anti-Keratin - Type I Cytoskeletal 19 antibody
Anti-Cytokeratin-19 antibody
Anti-Ck-19 antibody
Anti-Keratin-19 antibody
Anti-K19 antibody
Anti-KRT19 antibody

Information sourced from Uniprot.org

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