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![Anti-Keratin 18 antibody [C-04] (STJ16101024)](https://cdn11.bigcommerce.com/s-zso2xnchw9/images/stencil/124x110/products/149740/302484/STJ16101024_2__16909.1646940661.jpg?c=1 "Anti-Keratin 18 antibody [C-04] (STJ16101024)")
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Anti-Keratin 18 antibody [C-04] (STJ16101024)
SPECIFICATIONS
ClonalityMonoclonal
HostMouse
ConjugationUnconjugated
IsotypeIgG1k
ImmunogenA hybrid (BALB/c x B6) mouse was immunized with a cytoskeleton preparation of human A431 carcinoma cell line. Fusion partner: Sp2/0.
General Information
| Short Description | Mouse monoclonal anti-Keratin 18 for use in FC in Cat, Cow, Dog, Ferret, Goat, Hamster, Horse, Human, Marmoset, Mouse, Pig, Rat and Sheep samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | FC |
| Host | Mouse |
| Reactivity | Cat/Cow/Dog/Ferret/Goat/Hamster/Horse/Human/Marmoset/Mouse/Pig/Rat/Sheep |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | C-04 |
| Isotype | IgG1k |
| Conjugation | Unconjugated |
| Concentration | Can be provided as 100 µg/mL, 500 µg/mL or 1mg/mL. |
| Purification | Affinity purified from tissue culture. |
| Dilution Range | Flow Cytometry (1-2 µg/million cells in 0, 1 ml, fix cells in 4% PFA for 10 min, at 4°C, permeabilize with 0, 2% saponin or digitonin for 15 min, at 4°C). Immunoblotting (1-2 µg/ml). Immunofluorescence (0.5-1, 0 µg/ml). Immunohistology (1-2 µg/ml for |
| Formulation | PBS with 0.02% Sodium Azide. |
| Storage Instruction | Store for up to 1 year at 2-8°C upon receipt. |
Target Information
| Gene Symbol | KRTAP10-11 |
| Gene ID | 386678 |
| Uniprot ID | KR10B_HUMAN |
| Immunogen | A hybrid (BALB/c x B6) mouse was immunized with a cytoskeleton preparation of human A431 carcinoma cell line. Fusion partner: Sp2/0. |
Additional Info
| Tissue Specificity | Restricted to a narrow region of the hair fiber cuticle, lying approximately 20 cell layers above the apex of the dermal papilla of the hair root.not detected in any other tissues. |
| Function | In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin-associated proteins (KRTAP), which are essential for the formation of a rigid and resistant hair shaft through their extensive disulfide bond cross-linking with abundant cysteine residues of hair keratins. The matrix proteins include the high-sulfur and high-glycine-tyrosine keratins. |
| Protein Name | Keratin-Associated Protein 10-11High Sulfur Keratin-Associated Protein 10.11Keratin-Associated Protein 10.11Keratin-Associated Protein 18-11Keratin-Associated Protein 18.11 |
| Database Links | Reactome: R-HSA-6805567 |
| Cellular Localisation | |
| Alternative Antibody Names | Anti-Keratin-Associated Protein 10-11 antibodyAnti-High Sulfur Keratin-Associated Protein 10.11 antibodyAnti-Keratin-Associated Protein 10.11 antibodyAnti-Keratin-Associated Protein 18-11 antibodyAnti-Keratin-Associated Protein 18.11 antibodyAnti-KRTAP10-11 antibodyAnti-KAP10.11 antibodyAnti-KAP18-11 antibodyAnti-KRTAP10.11 antibodyAnti-KRTAP18-11 antibodyAnti-KRTAP18.11 antibody |
Information sourced from Uniprot.org