• Immunohistochemistry analysis of KDM7A in paraffin-embedded mouse lung tissue using KDM7A Rabbit polyclonal antibody (STJ11105555) at a dilution of 1:100 (40x lens). High pressure antigen retrieval was performed with 0. 01 M citrate buffer (pH 6. 0) prior to immunohistochemistry staining.
  • Immunohistochemistry analysis of KDM7A in paraffin-embedded mouse testis tissue using KDM7A Rabbit polyclonal antibody (STJ11105555) at a dilution of 1:100 (40x lens). High pressure antigen retrieval was performed with 0. 01 M citrate buffer (pH 6. 0) prior to immunohistochemistry staining.
  • Immunohistochemistry analysis of KDM7A in paraffin-embedded human liver cancer tissue using KDM7A Rabbit polyclonal antibody (STJ11105555) at a dilution of 1:100 (40x lens). High pressure antigen retrieval was performed with 0. 01 M citrate buffer (pH 6. 0) prior to immunohistochemistry staining.
  • Immunohistochemistry analysis of KDM7A in paraffin-embedded rat liver tissue using KDM7A Rabbit polyclonal antibody (STJ11105555) at a dilution of 1:100 (40x lens). High pressure antigen retrieval was performed with 0. 01 M citrate buffer (pH 6. 0) prior to immunohistochemistry staining.

Anti-KDM7A antibody (840-941) (STJ11105555)

SKU:
STJ11105555

£116.50 - £543.50
Current Stock:
Host: Rabbit
Applications: IHC
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-Lysine-Specific Demethylase 7a (840-941) is suitable for use in Immunohistochemistry research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.05% Proclin300, 50% Glycerol, pH7.3.
Purification: Affinity purification
Dilution Range: IHC-P 1:50-1:200
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: KDM7A
Gene ID: 80853
Uniprot ID: KDM7A_HUMAN
Immunogen Region: 840-941
Immunogen: A synthetic peptide corresponding to a sequence within amino acids 840-941 of human KDM7A (NP_085150.1).
Immunogen Sequence: VQSRNYVDSSGSSLQNGKYM QNSNLTSGACQISNGSLSPE RPVGETSFSVPLHPTKRPAS NPPPISNQATKGKRPKKGMA TAKQRLGKILKLNRNGHARF FV
Function Histone demethylase required for brain development. Specifically demethylates dimethylated 'Lys-9', 'Lys-27' and 'Lys-36' (H3K9me2, H3K27me2, H3K36me2, respectively) of histone H3 and monomethylated histone H4 'Lys-20' residue (H4K20Me1), thereby playing a central role in histone code. Specifically binds trimethylated 'Lys-4' of histone H3 (H3K4me3), affecting histone demethylase specificity: in presence of H3K4me3, it has no demethylase activity toward H3K9me2, while it has high activity toward H3K27me2. Demethylates H3K9me2 in absence of H3K4me3. Has activity toward H4K20Me1 only when nucleosome is used as a substrate and when not histone octamer is used as substrate.
Protein Name Lysine-Specific Demethylase 7a
Jmjc Domain-Containing Histone Demethylation Protein 1d
Lysine-Specific Demethylase 7
Histone H3-Dimethyl-L-Lysine9 Demethylase 7a
Database Links Reactome: R-HSA-3214842
Reactome: R-HSA-6802952
Cellular Localisation Nucleus
Alternative Antibody Names Anti-Lysine-Specific Demethylase 7a antibody
Anti-Jmjc Domain-Containing Histone Demethylation Protein 1d antibody
Anti-Lysine-Specific Demethylase 7 antibody
Anti-Histone H3-Dimethyl-L-Lysine9 Demethylase 7a antibody
Anti-KDM7A antibody
Anti-JHDM1D antibody
Anti-KDM7 antibody
Anti-KIAA1718 antibody

Information sourced from Uniprot.org

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