Anti-KDM5C IP antibody [SAA0206] (STJA0018721)
SPECIFICATIONS
ClonalityMonoclonal
HostMouse
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Mouse monoclonal Lysine-Specific Demethylase 5c antibody for use in ELISA, IF and IP in human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | ELISA/IF/IP |
| Host | Mouse |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO) MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS |
Product Properties
| Clonality | Monoclonal |
| Clone ID | SAA0206 |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | Protein A/G purified from cell culture supernatant |
| Formulation | 0.01M PBS, pH 7.4. |
| Storage Instruction | Suitable for storage at +4°C between 1-2 weeks For longer term store at-20°C for up to 12 months |
Target Information
| Gene Symbol | KDM5C |
| Gene ID | 8242 |
| Uniprot ID | KDM5C_HUMAN |
Additional Info
| Function | Histone demethylase that specifically demethylates 'Lys-4' of histone H3, thereby playing a central role in histone code. Does not demethylate histone H3 'Lys-9', H3 'Lys-27', H3 'Lys-36', H3 'Lys-79' or H4 'Lys-20'. Demethylates trimethylated and dimethylated but not monomethylated H3 'Lys-4'. Participates in transcriptional repression of neuronal genes by recruiting histone deacetylases and REST at neuron-restrictive silencer elements. Represses the CLOCK-BMAL1 heterodimer-mediated transcriptional activation of the core clock component PER2. |
| Protein Name | Lysine-Specific Demethylase 5cHistone Demethylase Jarid1cJumonji/Arid Domain-Containing Protein 1cProtein SmcxProtein Xe169Histone H3-Trimethyl-L-Lysine(4 Demethylase 5c |
| Database Links | Reactome: R-HSA-3214842 |
| Cellular Localisation | Nucleus |
| Alternative Antibody Names | Anti-Lysine-Specific Demethylase 5c antibodyAnti-Histone Demethylase Jarid1c antibodyAnti-Jumonji/Arid Domain-Containing Protein 1c antibodyAnti-Protein Smcx antibodyAnti-Protein Xe169 antibodyAnti-Histone H3-Trimethyl-L-Lysine(4 Demethylase 5c antibodyAnti-KDM5C antibodyAnti-DXS1272E antibodyAnti-JARID1C antibodyAnti-SMCX antibodyAnti-XE169 antibody |
Information sourced from Uniprot.org