Anti-KDM4D antibody (340-390) {FITC} (STJ501527)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationFITC
IsotypeIgG
ImmunogenSynthetic peptide taken within amino acid region 340-390 on human Jumonji domain containg 2D protein.
General Information
| Short Description | Rabbit polyclonal antibody anti-KDM4D (340-390) is suitable for use in ELISA, Immunoprecipitation and Western Blot research applications. |
| Applications | ELISA/IP/WB |
| Host | Rabbit |
| Reactivity | Human/Monkey |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | FITC |
| Concentration | 0.55-0.75 ยตg/ยตl |
| Purification | Affinity Purified |
| Dilution Range | WB: 1:500DB: 1:10, 000ELISA: 1:10, 000IP: 1:150 |
| Formulation | Contains Tris, HCl/Glycine buffer pH 7.4-7.8, 30% Glycerol and 0.5% BSA, along with cryo-protective agents, Hepes, and long-term preservatives (0.02% Sodium Azide). |
| Storage Instruction | Store at-20ยฐC for long term storage. Avoid freeze-thaw cycles. |
Target Information
| Gene Symbol | KDM4D |
| Gene ID | 55693 |
| Uniprot ID | KDM4D_HUMAN |
| Immunogen | Synthetic peptide taken within amino acid region 340-390 on human Jumonji domain containg 2D protein. |
| Immunogen Region | 340-390 |
Additional Info
| Post Translational Modifications | Ubiquitinated via 'Lys-63'-linked ubiquitin chains. Deubiquitinated by USP14 with the help of TRIM14 leading to stabilization. |
| Function | Histone demethylase that specifically demethylates 'Lys-9' of histone H3, thereby playing a central role in histone code. Does not demethylate histone H3 'Lys-4', H3 'Lys-27', H3 'Lys-36' nor H4 'Lys-20'. Demethylates both di- and trimethylated H3 'Lys-9' residue, while it has no activity on monomethylated residues. Demethylation of Lys residue generates formaldehyde and succinate. |
| Protein Name | Lysine-Specific Demethylase 4dJmjc Domain-Containing Histone Demethylation Protein 3dJumonji Domain-Containing Protein 2dHistone H3-Trimethyl-L-Lysine(9 Demethylase 4d |
| Database Links | Reactome: R-HSA-3214842 |
| Cellular Localisation | Nucleus |
| Alternative Antibody Names | Anti-Lysine-Specific Demethylase 4d antibodyAnti-Jmjc Domain-Containing Histone Demethylation Protein 3d antibodyAnti-Jumonji Domain-Containing Protein 2d antibodyAnti-Histone H3-Trimethyl-L-Lysine(9 Demethylase 4d antibodyAnti-KDM4D antibodyAnti-JHDM3D antibodyAnti-JMJD2D antibody |
Information sourced from Uniprot.org