Anti-KDM4B antibody [R08-9G9] (STJA0034506)
SPECIFICATIONS
ClonalityMonoclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenA synthetic peptide of human KDM4B/JMJD2B
General Information
| Short Description | Rabbit monoclonal anti-KDM4B for use in WB, IHC-F, IHC-P, ICC and IF in Human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IHC-F/IHC-P/ICC/IF |
| Host | Rabbit |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | R08-9G9 |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 0.3 mg/mL |
| Purification | Affinity Purified |
| Dilution Range | WB 1:500-1:1000IHC 1:50-1:100IF 1:50-1:200 |
| Formulation | 50mM Tris-Glycine (pH 7.4) , 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA |
| Storage Instruction | Store at 4°C short term. Aliquot and store at-20°C long term. Avoid freeze/thaw cycles. |
Target Information
| Gene Symbol | KDM4B |
| Gene ID | 23030 |
| Uniprot ID | KDM4B_HUMAN |
| Immunogen | A synthetic peptide of human KDM4B/JMJD2B |
Additional Info
| Function | Histone demethylase that specifically demethylates 'Lys-9' of histone H3, thereby playing a role in histone code. Does not demethylate histone H3 'Lys-4', H3 'Lys-27', H3 'Lys-36' nor H4 'Lys-20'. Only able to demethylate trimethylated H3 'Lys-9', with a weaker activity than KDM4A, KDM4C and KDM4D. Demethylation of Lys residue generates formaldehyde and succinate. Plays a critical role in the development of the central nervous system (CNS). |
| Protein Name | Lysine-Specific Demethylase 4bJmjc Domain-Containing Histone Demethylation Protein 3bJumonji Domain-Containing Protein 2bHistone H3-Trimethyl-L-Lysine(9 Demethylase 4b |
| Database Links | Reactome: R-HSA-3214842Reactome: R-HSA-5693565Reactome: R-HSA-9018519 |
| Cellular Localisation | Nucleus |
| Alternative Antibody Names | Anti-Lysine-Specific Demethylase 4b antibodyAnti-Jmjc Domain-Containing Histone Demethylation Protein 3b antibodyAnti-Jumonji Domain-Containing Protein 2b antibodyAnti-Histone H3-Trimethyl-L-Lysine(9 Demethylase 4b antibodyAnti-KDM4B antibodyAnti-JHDM3B antibodyAnti-JMJD2B antibodyAnti-KIAA0876 antibody |
Information sourced from Uniprot.org