Anti-KDEL antibody [R93-3J-9] (STJA0035430)
SPECIFICATIONS
ClonalityMonoclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenA synthesized peptide derived from human KDEL
General Information
| Short Description | Rabbit monoclonal anti-KDEL for use in WB, IHC-P, ICC, IF and FC in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IHC-P/ICC/IF/FC |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | R93-3J-9 |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Purification | Affinity Chromatography |
| Dilution Range | WB 1:500-1:1000IHC 1:100-1:200IF 1:50-1:200FC 1:50 |
| Formulation | Liquid in PBS, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Storage Instruction | Store at 4°C short term. Aliquot and store at-20°C long term. Avoid freeze/thaw cycles. |
Target Information
| Gene Symbol | KDELR1 |
| Gene ID | 10945 |
| Uniprot ID | ERD21_HUMAN |
| Immunogen | A synthesized peptide derived from human KDEL |
Additional Info
| Post Translational Modifications | Phosphorylation by PKA at Ser-209 is required for endoplasmic reticulum retention function. |
| Function | Receptor for the C-terminal sequence motif K-D-E-L that is present on endoplasmic reticulum resident proteins and that mediates their recycling from the Golgi back to the endoplasmic reticulum. |
| Protein Name | Er Lumen Protein-Retaining Receptor 1Kdel Endoplasmic Reticulum Protein Retention Receptor 1Kdel Receptor 1Putative Mapk-Activating Protein Pm23 |
| Database Links | Reactome: R-HSA-6807878Reactome: R-HSA-6811434 |
| Cellular Localisation | Golgi Apparatus MembraneMulti-Pass Membrane ProteinCytoplasmic VesicleCopi-Coated Vesicle MembraneEndoplasmic Reticulum MembraneEndoplasmic Reticulum-Golgi Intermediate Compartment MembraneLocalized In The Golgi In The Absence Of Bound Proteins With The Sequence Motif K-D-E-LTrafficks Back To The Endoplasmic Reticulum Together With Cargo Proteins Containing The Sequence Motif K-D-E-L |
| Alternative Antibody Names | Anti-Er Lumen Protein-Retaining Receptor 1 antibodyAnti-Kdel Endoplasmic Reticulum Protein Retention Receptor 1 antibodyAnti-Kdel Receptor 1 antibodyAnti-Putative Mapk-Activating Protein Pm23 antibodyAnti-KDELR1 antibodyAnti-ERD2.1 antibody |
Information sourced from Uniprot.org