| Host: |
Rabbit |
| Applications: |
IHC/ELISA |
| Reactivity: |
Human/Mouse |
| Note: |
FOR SCIENTIFIC EDUCATIONAL RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR OTHER MEDICAL APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-Btb/Poz Domain-Containing Adapter For Cul3-Mediated Rhoa Degradation Protein 1 is suitable for use in Immunohistochemistry and ELISA research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.05% NaN3 and 40% Glycerol, pH7.4 |
| Purification: |
Antigen affinity purification |
| Concentration: |
0.66 mg/mL |
| Dilution Range: |
IHC 1:50-1:300 |
| Storage Instruction: |
Store at-20°C for long term, and avoid freeze-thaw cycles. |
| Tissue Specificity | Expressed in a wide variety of tissues. |
| Function | Substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex required for synaptic transmission. The BCR(KCTD13) E3 ubiquitin ligase complex mediates the ubiquitination of RHOA, leading to its degradation by the proteasome Degradation of RHOA regulates the actin cytoskeleton and promotes synaptic transmission. |
| Protein Name | Btb/Poz Domain-Containing Adapter For Cul3-Mediated Rhoa Degradation Protein 1Hbacurd1Btb/Poz Domain-Containing Protein Kctd13Polymerase Delta-Interacting Protein 1Tnfaip1-Like Protein |
| Database Links | Reactome: R-HSA-9696264Reactome: R-HSA-9696270 |
| Cellular Localisation | Nucleus |
| Alternative Antibody Names | Anti-Btb/Poz Domain-Containing Adapter For Cul3-Mediated Rhoa Degradation Protein 1 antibodyAnti-Hbacurd1 antibodyAnti-Btb/Poz Domain-Containing Protein Kctd13 antibodyAnti-Polymerase Delta-Interacting Protein 1 antibodyAnti-Tnfaip1-Like Protein antibodyAnti-KCTD13 antibodyAnti-BACURD1 antibodyAnti-PDIP1 antibodyAnti-POLDIP1 antibodyAnti-FKSG86 antibodyAnti-PP6832 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
