Anti-KCNU1 antibody (820-870 aa) (STJ13101656)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenA synthetic peptide from aa region 820-870 of mouse KCNU1 conjugated to blue carrier protein was used as the antigen.
General Information
| Short Description | Rabbit polyclonal anti-KCNU1 (820-870 aa) for use in IHC and WB in Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | IHC/WB |
| Host | Rabbit |
| Reactivity | Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Purification | IgG purified |
| Dilution Range | IHC, WB (confirmed by recombinant protein). A dilution of 1:3000 to 1:5000 is recommended. The optimal dilution should be determined by the end user. Not yet tested in other applications. |
| Formulation | Lyophilised |
| Storage Instruction | Maintain the lyophilised/reconstituted antibodies frozen at-20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, Glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles. |
Target Information
| Gene Symbol | Kcnu1 |
| Gene ID | 16532 |
| Uniprot ID | KCNU1_MOUSE |
| Immunogen | A synthetic peptide from aa region 820-870 of mouse KCNU1 conjugated to blue carrier protein was used as the antigen. |
| Immunogen Region | 820-870 aa |
| Specificity | Specific for KCNU1. |
Additional Info
| Function | Testis-specific potassium channel activated by both intracellular pH and membrane voltage that mediates export of K(+). Represents the primary spermatozoan K(+) current. The channel underlies a pH-triggered membrane hyperpolarization during the process of sperm capacitation, as sperm encounter the alkaline environment near the ovum in the female reproductive tract, thereby playing an essential for male fertility. |
| Protein Name | Potassium Channel Subfamily U Member 1Calcium-Activated Potassium Channel Subunit Alpha-3Calcium-Activated Potassium Channel - Subfamily M Subunit Alpha-3Pore-Forming Subunit Of The Sperm-Specific Alkalization Activated K(+ CurrentKsperSlowpoke Homolog 3Mslo3Ph-Sensitive Maxi Potassium Channel |
| Database Links | Reactome: R-MMU-1300642 |
| Cellular Localisation | Isoform 1: Cell MembraneMulti-Pass Membrane ProteinIsoform 2: Cytoplasm |
| Alternative Antibody Names | Anti-Potassium Channel Subfamily U Member 1 antibodyAnti-Calcium-Activated Potassium Channel Subunit Alpha-3 antibodyAnti-Calcium-Activated Potassium Channel - Subfamily M Subunit Alpha-3 antibodyAnti-Pore-Forming Subunit Of The Sperm-Specific Alkalization Activated K(+ Current antibodyAnti-Ksper antibodyAnti-Slowpoke Homolog 3 antibodyAnti-Mslo3 antibodyAnti-Ph-Sensitive Maxi Potassium Channel antibodyAnti-Kcnu1 antibodyAnti-Kcnma3 antibodyAnti-Ksper antibodyAnti-Slo3 antibody |
Information sourced from Uniprot.org