Anti-KCNK17 antibody (271-320 aa) (STJ95904)

SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenThe antiserum was produced against synthesized peptide derived from the human KCNK17 at the amino acid range 271-320
STJ95904
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General Information

Short DescriptionRabbit polyclonal anti-Potassium channel subfamily K member 17 channel 4 channel 2 (271-320 aa) for use in WB and ELISA in Human, Rat and Mouse samples. Datasheet included with dilution recommendations, and related reagents.
ApplicationsWB/ELISA
HostRabbit
ReactivityHuman/Rat/Mouse
NoteSTRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Product Properties

ClonalityPolyclonal
IsotypeIgG
ConjugationUnconjugated
Concentration1 mg/mL
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Dilution RangeWB 1:500-1:2000
ELISA 1:20000
FormulationLiquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Storage InstructionStore at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.

Target Information

Gene SymbolKCNK17
Gene ID89822
Uniprot IDKCNKH_HUMAN
ImmunogenThe antiserum was produced against synthesized peptide derived from the human KCNK17 at the amino acid range 271-320
Immunogen Region271-320 aa
SpecificityTALK-2 Polyclonal Antibody detects endogenous levels of TALK-2 protein.

Additional Info

Function K(+) channel that conducts voltage-dependent outward rectifying currents upon membrane depolarization. Voltage sensing is coupled to K(+) electrochemical gradient in an 'ion flux gating' mode where outward but not inward ion flow opens the gate. Homo- and heterodimerizes to form functional channels with distinct regulatory and gating properties. Present in the cardiac conduction system where it may regulate action potential duration and beating frequency of cardiac myocytes. Permeable to other monovalent cations such as Rb(+) and Cs(+).
Protein Name Potassium Channel Subfamily K Member 17
2p Domain Potassium Channel Talk-2
Acid-Sensitive Potassium Channel Protein Task-4
Twik-Related Acid-Sensitive K(+ Channel 4
Twik-Related Alkaline Ph-Activated K(+ Channel 2
Talk-2
Database Links Reactome: R-HSA-1299361
Reactome: R-HSA-5576886
Cellular Localisation Cell Membrane
Multi-Pass Membrane Protein
Alternative Antibody Names Anti-Potassium Channel Subfamily K Member 17 antibody
Anti-2p Domain Potassium Channel Talk-2 antibody
Anti-Acid-Sensitive Potassium Channel Protein Task-4 antibody
Anti-Twik-Related Acid-Sensitive K(+ Channel 4 antibody
Anti-Twik-Related Alkaline Ph-Activated K(+ Channel 2 antibody
Anti-Talk-2 antibody
Anti-KCNK17 antibody
Anti-TALK2 antibody
Anti-TASK4 antibody
Anti-UNQ5816 antibody
Anti-PRO19634 antibody

Information sourced from Uniprot.org

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