| Host: |
Rabbit |
| Applications: |
WB/ELISA |
| Reactivity: |
Human/Rat/Mouse |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-ATP-sensitive inward rectifier potassium channel 8 channel Kir6.1 (50-130 aa) is suitable for use in Western Blot and ELISA research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
Liquid in PBS containing 50% Glycerol and 0.02% Sodium Azide. |
| Purification: |
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: |
1 mg/mL |
| Dilution Range: |
WB 1:500-2000ELISA 1:5000-20000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
KCNJ8 |
| Gene ID: |
3764 |
| Uniprot ID: |
KCNJ8_HUMAN |
| Immunogen Region: |
50-130 aa |
| Specificity: |
IRK8 Polyclonal Antibody detects endogenous levels of protein. |
| Immunogen: |
Synthesized peptide derived from the human protein at the amino acid range 50-130 |
| Function | This potassium channel is controlled by G proteins. Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium.as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due to the blockage of outward current by internal magnesium. Can be blocked by external barium. |
| Protein Name | Atp-Sensitive Inward Rectifier Potassium Channel 8Inward Rectifier K(+ Channel Kir6.1Potassium Channel - Inwardly Rectifying Subfamily J Member 8Ukatp-1 |
| Database Links | Reactome: R-HSA-1296025 |
| Cellular Localisation | MembraneMulti-Pass Membrane Protein |
| Alternative Antibody Names | Anti-Atp-Sensitive Inward Rectifier Potassium Channel 8 antibodyAnti-Inward Rectifier K(+ Channel Kir6.1 antibodyAnti-Potassium Channel - Inwardly Rectifying Subfamily J Member 8 antibodyAnti-Ukatp-1 antibodyAnti-KCNJ8 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
