Anti-KCNJ8 antibody (50-130 aa) (STJ190597)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthesized peptide derived from the human protein at the amino acid range 50-130
General Information
| Short Description | Rabbit polyclonal anti-ATP-sensitive inward rectifier potassium channel 8 channel Kir6.1 (50-130 aa) for use in WB and ELISA in Human, Rat and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Human/Rat/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-2000ELISA 1:5000-20000 |
| Formulation | Liquid in PBS containing 50% Glycerol and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20ยฐC for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | KCNJ8 |
| Gene ID | 3764 |
| Uniprot ID | KCNJ8_HUMAN |
| Immunogen | Synthesized peptide derived from the human protein at the amino acid range 50-130 |
| Immunogen Region | 50-130 aa |
| Specificity | IRK8 Polyclonal Antibody detects endogenous levels of protein. |
Additional Info
| Function | Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium.as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due to the blockage of outward current by internal magnesium. This channel is activated by internal ATP and can be blocked by external barium. Can form a sulfonylurea-sensitive but ATP-insensitive potassium channel with ABCC9. |
| Protein Name | Atp-Sensitive Inward Rectifier Potassium Channel 8Inward Rectifier K(+ Channel Kir6.1Potassium Channel - Inwardly Rectifying Subfamily J Member 8Ukatp-1 |
| Database Links | Reactome: R-HSA-1296025 |
| Cellular Localisation | MembraneMulti-Pass Membrane Protein |
| Alternative Antibody Names | Anti-Atp-Sensitive Inward Rectifier Potassium Channel 8 antibodyAnti-Inward Rectifier K(+ Channel Kir6.1 antibodyAnti-Potassium Channel - Inwardly Rectifying Subfamily J Member 8 antibodyAnti-Ukatp-1 antibodyAnti-KCNJ8 antibody |
Information sourced from Uniprot.org