• STJ71167 (0. 01µg/ml) staining of Human Muscle lysate (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.

Anti-Kcnj11/Kir6.2 antibody (Internal) (STJ71167)

SKU:
STJ71167-100

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Host: Goat
Applications: Pep-ELISA/WB/IHC
Reactivity: Human/Mouse/Rat/Dog
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Goat polyclonal antibody anti-Kcnj11/Kir6.2 (Internal) is suitable for use in ELISA, Western Blot and Immunohistochemistry research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA
Purification: Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Concentration: 0.5 mg/mL
Dilution Range: WB-0.01-0.03µg/ml
IHC-Recommended concentration, 3-5µg/ml
ELISA-antibody detection limit dilution 1:64000.
Storage Instruction: Store at-20°C on receipt and minimise freeze-thaw cycles.
Gene Symbol: KCNJ11
Gene ID: 3767
Uniprot ID: KCJ11_HUMAN
Immunogen Region: Internal
Accession Number: NP_034732.1
Immunogen Sequence: ERRARFVSKKGNC
Function This receptor is controlled by G proteins. Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium.as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due to the blockage of outward current by internal magnesium. Can be blocked by extracellular barium. Subunit of ATP-sensitive potassium channels (KATP). Can form cardiac and smooth muscle-type KATP channels with ABCC9. KCNJ11 forms the channel pore while ABCC9 is required for activation and regulation.
Protein Name Atp-Sensitive Inward Rectifier Potassium Channel 11
Ikatp
Inward Rectifier K(+ Channel Kir6.2
Potassium Channel - Inwardly Rectifying Subfamily J Member 11
Database Links Reactome: R-HSA-1296025
Reactome: R-HSA-382556
Reactome: R-HSA-422356
Reactome: R-HSA-5578775
Reactome: R-HSA-5678420
Reactome: R-HSA-5683177
Cellular Localisation Membrane
Multi-Pass Membrane Protein
Alternative Antibody Names Anti-Atp-Sensitive Inward Rectifier Potassium Channel 11 antibody
Anti-Ikatp antibody
Anti-Inward Rectifier K(+ Channel Kir6.2 antibody
Anti-Potassium Channel - Inwardly Rectifying Subfamily J Member 11 antibody
Anti-KCNJ11 antibody

Information sourced from Uniprot.org

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