Anti-KCNIP4 antibody (STJA0008578)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthesized peptide derived from human KCNIP4
General Information
| Short Description | Rabbit polyclonal anti-Kv channel-interacting protein 4 for use in WB in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | KCNIP4 |
| Gene ID | 80333 |
| Uniprot ID | KCIP4_HUMAN |
| Immunogen | Synthesized peptide derived from human KCNIP4 |
| Specificity | This antibody detects endogenous levels of KCNIP4 at Human, Mouse, Rat |
Additional Info
| Function | Regulatory subunit of Kv4/D (Shal)-type voltage-gated rapidly inactivating A-type potassium channels. Modulates KCND2 channel density, inactivation kinetics and rate of recovery from inactivation in a calcium-dependent and isoform-specific manner. Modulates KCND3/Kv4.3 currents. Isoform 4 does not increase KCND2 expression at the cell membrane. Isoform 4 retains KCND3 in the endoplasmic reticulum and negatively regulates its expression at the cell membrane. |
| Protein Name | Kv Channel-Interacting Protein 4Kchip4A-Type Potassium Channel Modulatory Protein 4Calsenilin-Like ProteinPotassium Channel-Interacting Protein 4 |
| Database Links | Reactome: R-HSA-5576894 |
| Cellular Localisation | Cell MembranePeripheral Membrane ProteinCytoplasmPeroxisomeIsoform 4: Endoplasmic Reticulum |
| Alternative Antibody Names | Anti-Kv Channel-Interacting Protein 4 antibodyAnti-Kchip4 antibodyAnti-A-Type Potassium Channel Modulatory Protein 4 antibodyAnti-Calsenilin-Like Protein antibodyAnti-Potassium Channel-Interacting Protein 4 antibodyAnti-KCNIP4 antibodyAnti-CALP antibodyAnti-KCHIP4 antibody |
Information sourced from Uniprot.org