Anti-KCNIP2 antibody (N-Term) (STJ13101296)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenA synthetic peptide from n-terminal region of mouse KCNIP2 (Potassium channel-interacting protein 2) conjugated to an immunogenic carrier protein was used as the antigen.
General Information
| Short Description | Rabbit polyclonal anti-KCNIP2 (N-Term) for use in IHC and WB in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | IHC/WB |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Purification | IgG purified |
| Dilution Range | IHC, WB (confirmed by recombinant protein). A dilution of 1:300 to 1:2000 is recommended. The optimal dilution should be determined by the end user. Not tested in other applications. |
| Formulation | Lyophilised |
| Storage Instruction | Maintain the lyophilised/reconstituted antibodies frozen at-20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, Glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles. |
Target Information
| Gene Symbol | KCNIP2 |
| Gene ID | 30819 |
| Uniprot ID | KCIP2_HUMAN |
| Immunogen | A synthetic peptide from n-terminal region of mouse KCNIP2 (Potassium channel-interacting protein 2) conjugated to an immunogenic carrier protein was used as the antigen. |
| Immunogen Region | N-Term |
| Specificity | Specific for KCNIP2. |
Additional Info
| Post Translational Modifications | Palmitoylated. Palmitoylation enhances association with the plasma membrane. |
| Function | Regulatory subunit of Kv4/D (Shal)-type voltage-gated rapidly inactivating A-type potassium channels. Modulates channel density, inactivation kinetics and rate of recovery from inactivation in a calcium-dependent and isoform-specific manner. Involved in KCND2 and KCND3 trafficking to the cell surface. May be required for the expression of I(To) currents in the heart. |
| Protein Name | A-Type Potassium Channel Modulatory Protein Kcnip2Cardiac Voltage-Gated Potassium Channel Modulatory SubunitKv Channel-Interacting Protein 2Kchip2Potassium Channel-Interacting Protein 2 |
| Database Links | Reactome: R-HSA-5576894 |
| Cellular Localisation | Isoform 1: Cell MembraneLipid-AnchorDetected On Lipid RaftsIsoform 2: Cell MembraneIsoform 6: Cell Membrane |
| Alternative Antibody Names | Anti-A-Type Potassium Channel Modulatory Protein Kcnip2 antibodyAnti-Cardiac Voltage-Gated Potassium Channel Modulatory Subunit antibodyAnti-Kv Channel-Interacting Protein 2 antibodyAnti-Kchip2 antibodyAnti-Potassium Channel-Interacting Protein 2 antibodyAnti-KCNIP2 antibodyAnti-KCHIP2 antibody |
Information sourced from Uniprot.org