Anti-KCNIP1 antibody (N-Term) (STJ13101295)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenA synthetic peptide from n-terminal region of rat KCNIP1, isoform 1 conjugated to an immunogenic carrier protein was used as the antigen.
General Information
| Short Description | Rabbit polyclonal anti-KCNIP1 (N-Term) for use in IHC and WB in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | IHC/WB |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Purification | IgG purified |
| Dilution Range | IHC, WB (confirmed by recombinant protein). A dilution of 1:300 to 1:2000 is recommended. The optimal dilution should be determined by the end user. Not tested in other applications. |
| Formulation | Lyophilised |
| Storage Instruction | Maintain the lyophilised/reconstituted antibodies frozen at-20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, Glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles. |
Target Information
| Gene Symbol | KCNIP1 |
| Gene ID | 30820 |
| Uniprot ID | KCIP1_HUMAN |
| Immunogen | A synthetic peptide from n-terminal region of rat KCNIP1, isoform 1 conjugated to an immunogenic carrier protein was used as the antigen. |
| Immunogen Region | N-Term |
| Specificity | Specific for KCNIP1. |
Additional Info
| Function | Regulatory subunit of Kv4/D (Shal)-type voltage-gated rapidly inactivating A-type potassium channels. Regulates channel density, inactivation kinetics and rate of recovery from inactivation in a calcium-dependent and isoform-specific manner. In vitro, modulates KCND1/Kv4.1 and KCND2/Kv4.2 currents. Increases the presence of KCND2 at the cell surface. |
| Protein Name | A-Type Potassium Channel Modulatory Protein Kcnip1Kv Channel-Interacting Protein 1Kchip1Potassium Channel-Interacting Protein 1Vesicle Apc-Binding Protein |
| Database Links | Reactome: R-HSA-5576894 |
| Cellular Localisation | Cell MembranePeripheral Membrane ProteinCytoplasmCell ProjectionDendrite |
| Alternative Antibody Names | Anti-A-Type Potassium Channel Modulatory Protein Kcnip1 antibodyAnti-Kv Channel-Interacting Protein 1 antibodyAnti-Kchip1 antibodyAnti-Potassium Channel-Interacting Protein 1 antibodyAnti-Vesicle Apc-Binding Protein antibodyAnti-KCNIP1 antibodyAnti-KCHIP1 antibodyAnti-VABP antibody |
Information sourced from Uniprot.org