Anti-KCNH6 antibody (C-Term) (STJ13101622)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenA synthetic peptide from the c-terminal of human KCNH6 (Potassium voltage-gated channel subfamily H member 6) conjugated to an immunogenic carrier protein was used as the immunogen.
General Information
| Short Description | Rabbit polyclonal anti-KCNH6 (C-Term) for use in IHC and WB in Human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | IHC/WB |
| Host | Rabbit |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Purification | IgG purified |
| Dilution Range | IHC, WB. A dilution of 1:300 to 1:2000 is recommended. The optimal dilution should be determined by the end user. Not yet tested in other applications. |
| Formulation | Lyophilised |
| Storage Instruction | Maintain the lyophilised/reconstituted antibodies frozen at-20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, Glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles. |
Target Information
| Gene Symbol | KCNH6 |
| Gene ID | 81033 |
| Uniprot ID | KCNH6_HUMAN |
| Immunogen | A synthetic peptide from the c-terminal of human KCNH6 (Potassium voltage-gated channel subfamily H member 6) conjugated to an immunogenic carrier protein was used as the immunogen. |
| Immunogen Region | C-Term |
| Specificity | Specific for KCNH6. |
Additional Info
| Function | Pore-forming (alpha) subunit of voltage-gated inwardly rectifying potassium channel. Characterized by unusual gating kinetics by producing relatively small outward currents during membrane depolarization and large inward currents during subsequent repolarization which reflect a rapid inactivation during depolarization and quick recovery from inactivation but slow deactivation (closing) during repolarization. Activates even more slowly than KCNH2. |
| Protein Name | Voltage-Gated Inwardly Rectifying Potassium Channel Kcnh6Ether-A-Go-Go-Related Gene Potassium Channel 2Erg-2Eag-Related Protein 2Ether-A-Go-Go-Related Protein 2Herg-2Herg2Potassium Voltage-Gated Channel Subfamily H Member 6Voltage-Gated Potassium Channel Subunit Kv11.2 |
| Database Links | Reactome: R-HSA-1296072 |
| Cellular Localisation | Cell MembraneMulti-Pass Membrane Protein |
| Alternative Antibody Names | Anti-Voltage-Gated Inwardly Rectifying Potassium Channel Kcnh6 antibodyAnti-Ether-A-Go-Go-Related Gene Potassium Channel 2 antibodyAnti-Erg-2 antibodyAnti-Eag-Related Protein 2 antibodyAnti-Ether-A-Go-Go-Related Protein 2 antibodyAnti-Herg-2 antibodyAnti-Herg2 antibodyAnti-Potassium Voltage-Gated Channel Subfamily H Member 6 antibodyAnti-Voltage-Gated Potassium Channel Subunit Kv11.2 antibodyAnti-KCNH6 antibodyAnti-ERG2 antibody |
Information sourced from Uniprot.org